Purushothama Rao Tata
Associate Professor of Cell Biology
Lung regenerationLung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology
Appointments and Affiliations
- Associate Professor of Cell Biology
- Associate Professor in Medicine
- Affiliate of the Duke Regeneration Center
- Member of the Duke Cancer Institute
Contact Information
- Email Address: purushothamarao.tata@duke.edu
- Websites:
Education
- Ph.D. University of Ulm (Germany), 2011
Awards, Honors, and Distinctions
- Rising Star Award. International Society for Regenerative Biology. 2022
- Whitehead Scholar Award. Duke University School of Medicine. 2016
- NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
- The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014
Courses Taught
- PHARM 730: Stem Cell Course
- MOLCAN 730: Stem Cell Course
- DSCB 720: Stem Cell Course
- CMB 720: Modern Techniques in Cell and Molecular Biology
- CMB 710E: Cell & Molecular Biology Module V
- CMB 710D: Cell & Molecular Biology Module IV
- CELLBIO 730: Stem Cell Course
- CELLBIO 493: Research Independent Study
In the News
- Study Provides Clues to Developing Better Treatments for Lung Damage (Nov 15, 2023 | School of Medicine)
- Tata to Receive International Society for Regenerative Biology Rising Star Award (Jul 19, 2022)
- NIH-Directors blog- Mini-Lungs in a Lab Dish Mimic Early COVID-19 Infection (Nov 18, 2020 | NIH-Directors blog)
- Lab-Grown Mini-Lungs Mimic the Real Thing – Right Down to Covid Infection (Oct 22, 2020)
- SARS-CoV-2 Targets Many Cell Types, Analysis of Single-Cell Data Suggests (May 10, 2020 | www.hhmi.org)
- Scientists Find Stomach Cells In Lung Cancer (Mar 26, 2018)
- Purushothama Tata: So Many Ideas, So Little Time (Oct 2, 2016)
Representative Publications
- Forrester, MT; Egol, JR; Tata, A; Tata, PR; Foster, MW, Analysis of Protein Cysteine Acylation Using a Modified Suspension Trap (Acyl-Trap). (2024) [10.1101/2024.03.23.586403] [abs].
- Chioccioli, M; Liu, S; Magruder, S; Tata, A; Borriello, L; McDonough, JE; Konkimalla, A; Kim, S-H; Nouws, J; Gonzalez, DG; Traub, B; Ye, X; Yang, T; Entenberg, DR; Krishnaswamy, S; Hendry, CE; Kaminski, N; Tata, PR; Sauler, M, Stem cell migration drives lung repair in living mice., Dev Cell (2024) [10.1016/j.devcel.2024.02.003] [abs].
- Karmaus, PWF; Tata, A; Meacham, JM; Day, F; Thrower, D; Tata, PR; Fessler, MB, Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates., Am J Respir Cell Mol Biol, vol 69 no. 6 (2023), pp. 623-637 [10.1165/rcmb.2023-0077OC] [abs].
- Vazquez-Armendariz, AI; Tata, PR, Recent advances in lung organoid development and applications in disease modeling., J Clin Invest, vol 133 no. 22 (2023) [10.1172/JCI170500] [abs].
- Konkimalla, A; Konishi, S; Macadlo, L; Kobayashi, Y; Farino, ZJ; Miyashita, N; El Haddad, L; Morowitz, J; Barkauskas, CE; Agarwal, P; Souma, T; ElMallah, MK; Tata, A; Tata, PR, Transitional cell states sculpt tissue topology during lung regeneration., Cell Stem Cell, vol 30 no. 11 (2023), pp. 1486-1502.e9 [10.1016/j.stem.2023.10.001] [abs].