Purushothama Rao Tata

Purushothama Rao Tata

Assistant Professor of Cell Biology

Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology

Appointments and Affiliations

  • Assistant Professor of Cell Biology
  • Assistant Professor in Medicine
  • Member of the Duke Cancer Institute
  • Affiliate of the Duke Regeneration Center

Contact Information


  • Ph.D. University of Ulm (Germany), 2011

Awards, Honors, and Distinctions

  • Rising Star Award. International Society for Regenerative Biology. 2022
  • Whitehead Scholar Award. Duke University School of Medicine. 2016
  • NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
  • The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014

Courses Taught

  • CELLBIO 493: Research Independent Study
  • CELLBIO 730: Stem Cell Course
  • CMB 710D: Cell & Molecular Biology Module IV
  • CMB 710E: Cell & Molecular Biology Module V
  • DSCB 720: Stem Cell Course
  • MOLCAN 730: Stem Cell Course
  • PHARM 730: Stem Cell Course

In the News

Representative Publications

  • El Haddad, L; Lai, E; Murthy, PKL; Biswas, DD; Soufny, R; Roger, AL; Tata, PR; ElMallah, MK, GAA deficiency disrupts distal airway cells in Pompe disease., Am J Physiol Lung Cell Mol Physiol, vol 325 no. 3 (2023), pp. L288-L298 [10.1152/ajplung.00032.2023] [abs].
  • Konkimalla, A; Elmore, Z; Konishi, S; Macadlo, L; Katsura, H; Tata, A; Asokan, A; Tata, PR, Efficient Adeno-associated Virus-mediated Transgenesis in Alveolar Stem Cells and Associated Niches., Am J Respir Cell Mol Biol, vol 69 no. 3 (2023), pp. 255-265 [10.1165/rcmb.2022-0424MA] [abs].
  • , An interview with Purushothama Rao Tata., Development, vol 150 no. 15 (2023) [10.1242/dev.202164] [abs].
  • Karmaus, PWF; Tata, A; Meacham, JM; Day, F; Thrower, D; Tata, PR; Fessler, MB, Meta-Analysis of COVID-19 Bronchoalveolar Lavage scRNA-Seq Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates., Am J Respir Cell Mol Biol (2023) [10.1165/rcmb.2023-0077OC] [abs].
  • Conchola, AS; Frum, T; Xiao, Z; Hsu, PP; Kaur, K; Downey, MS; Hein, RFC; Miller, AJ; Tsai, Y-H; Wu, A; Holloway, EM; Anand, A; Murthy, PKL; Glass, I; Tata, PR; Spence, JR, Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung., Proc Natl Acad Sci U S A, vol 120 no. 24 (2023) [10.1073/pnas.2210113120] [abs].