Purushothama Rao Tata

Purushothama Rao Tata

Associate Professor of Cell Biology

Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology

Appointments and Affiliations

  • Associate Professor of Cell Biology
  • Associate Professor in Medicine
  • Affiliate of the Duke Regeneration Center
  • Member of the Duke Cancer Institute

Contact Information


  • Ph.D. University of Ulm (Germany), 2011

Awards, Honors, and Distinctions

  • Rising Star Award. International Society for Regenerative Biology. 2022
  • Whitehead Scholar Award. Duke University School of Medicine. 2016
  • NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
  • The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014

Courses Taught

  • PHARM 730: Stem Cell Course
  • MOLCAN 730: Stem Cell Course
  • DSCB 720: Stem Cell Course
  • CMB 720: Modern Techniques in Cell and Molecular Biology
  • CMB 710E: Cell & Molecular Biology Module V
  • CMB 710D: Cell & Molecular Biology Module IV
  • CELLBIO 730: Stem Cell Course
  • CELLBIO 493: Research Independent Study

In the News

Representative Publications

  • Forrester, MT; Egol, JR; Tata, A; Tata, PR; Foster, MW, Analysis of Protein Cysteine Acylation Using a Modified Suspension Trap (Acyl-Trap). (2024) [10.1101/2024.03.23.586403] [abs].
  • Kooistra, T; Saez, B; Roche, M; Egea-Zorrilla, A; Li, D; Anketell, D; Nguyen, N; Villoria, J; Gillis, J; Petri, E; Vera, L; Blasco-Iturri, Z; Smith, NP; Alladina, J; Zhang, Y; Vinarsky, V; Shivaraju, M; Sheng, SL; Gonzalez-Celeiro, M; Mou, H; Waghray, A; Lin, B; Paksa, A; Yanger, K; Tata, PR; Zhao, R; Causton, B; Zulueta, JJ; Prosper, F; Cho, JL; Villani, A-C; Haber, A; Rajagopal, J; Medoff, BD; Pardo-Saganta, A, Airway basal stem cells are necessary for the maintenance of functional intraepithelial airway macrophages., bioRxiv (2024) [10.1101/2024.06.25.600501] [abs].
  • Meganck, RM; Edwards, CE; Mallory, ML; Lee, RE; Dang, H; Bailey, AB; Wykoff, JA; Gallant, SC; Zhu, DR; Yount, BL; Kato, T; Shaffer, KM; Nakano, S; Cawley, AM; Sontake, V; Wang, JR; Hagan, RS; Miller, MB; Tata, PR; Randell, SH; Tse, LV; Ehre, C; Okuda, K; Boucher, RC; Baric, RS, SARS-CoV-2 variant of concern fitness and adaptation in primary human airway epithelia., Cell Rep, vol 43 no. 4 (2024) [10.1016/j.celrep.2024.114076] [abs].
  • Chioccioli, M; Liu, S; Magruder, S; Tata, A; Borriello, L; McDonough, JE; Konkimalla, A; Kim, S-H; Nouws, J; Gonzalez, DG; Traub, B; Ye, X; Yang, T; Entenberg, DR; Krishnaswamy, S; Hendry, CE; Kaminski, N; Tata, PR; Sauler, M, Stem cell migration drives lung repair in living mice., Dev Cell, vol 59 no. 7 (2024), pp. 830-840.e4 [10.1016/j.devcel.2024.02.003] [abs].
  • Karmaus, PWF; Tata, A; Meacham, JM; Day, F; Thrower, D; Tata, PR; Fessler, MB, Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates., Am J Respir Cell Mol Biol, vol 69 no. 6 (2023), pp. 623-637 [10.1165/rcmb.2023-0077OC] [abs].