Purushothama Rao Tata
Assistant Professor of Cell Biology
Lung regenerationLung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology
Appointments and Affiliations
- Assistant Professor of Cell Biology
- Assistant Professor in Medicine
- Member of the Duke Cancer Institute
- Affiliate of the Duke Regeneration Center
Contact Information
- Email Address: purushothamarao.tata@duke.edu
- Websites:
Education
- Ph.D. University of Ulm (Germany), 2011
Awards, Honors, and Distinctions
- Rising Star Award. International Society for Regenerative Biology. 2022
- Whitehead Scholar Award. Duke University School of Medicine. 2016
- NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
- The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014
Courses Taught
- CELLBIO 493: Research Independent Study
- CELLBIO 730: Stem Cell Course
- CMB 710D: Cell & Molecular Biology Module IV
- CMB 710E: Cell & Molecular Biology Module V
- DSCB 720: Stem Cell Course
- MOLCAN 730: Stem Cell Course
- PHARM 730: Stem Cell Course
In the News
- Tata to Receive International Society for Regenerative Biology Rising Star Award (Jul 20, 2022)
- NIH-Directors blog- Mini-Lungs in a Lab Dish Mimic Early COVID-19 Infection (Nov 19, 2020 | NIH-Directors blog)
- Lab-Grown Mini-Lungs Mimic the Real Thing – Right Down to Covid Infection (Oct 22, 2020)
- SARS-CoV-2 Targets Many Cell Types, Analysis of Single-Cell Data Suggests (May 11, 2020 | www.hhmi.org)
- Scientists Find Stomach Cells In Lung Cancer (Mar 26, 2018)
- Purushothama Tata: So Many Ideas, So Little Time (Oct 2, 2016)
Representative Publications
- El Haddad, L; Lai, E; Murthy, PKL; Biswas, DD; Soufny, R; Roger, AL; Tata, PR; ElMallah, MK, GAA deficiency disrupts distal airway cells in Pompe disease., Am J Physiol Lung Cell Mol Physiol, vol 325 no. 3 (2023), pp. L288-L298 [10.1152/ajplung.00032.2023] [abs].
- Konkimalla, A; Elmore, Z; Konishi, S; Macadlo, L; Katsura, H; Tata, A; Asokan, A; Tata, PR, Efficient Adeno-associated Virus-mediated Transgenesis in Alveolar Stem Cells and Associated Niches., Am J Respir Cell Mol Biol, vol 69 no. 3 (2023), pp. 255-265 [10.1165/rcmb.2022-0424MA] [abs].
- , An interview with Purushothama Rao Tata., Development, vol 150 no. 15 (2023) [10.1242/dev.202164] [abs].
- Karmaus, PWF; Tata, A; Meacham, JM; Day, F; Thrower, D; Tata, PR; Fessler, MB, Meta-Analysis of COVID-19 Bronchoalveolar Lavage scRNA-Seq Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates., Am J Respir Cell Mol Biol (2023) [10.1165/rcmb.2023-0077OC] [abs].
- Conchola, AS; Frum, T; Xiao, Z; Hsu, PP; Kaur, K; Downey, MS; Hein, RFC; Miller, AJ; Tsai, Y-H; Wu, A; Holloway, EM; Anand, A; Murthy, PKL; Glass, I; Tata, PR; Spence, JR, Regionally distinct progenitor cells in the lower airway give rise to neuroendocrine and multiciliated cells in the developing human lung., Proc Natl Acad Sci U S A, vol 120 no. 24 (2023) [10.1073/pnas.2210113120] [abs].