Hashim Al-Hashimi

Hashim Al-Hashimi

Adjunct Professor in the Department of Biochemistry

Appointments and Affiliations

  • Adjunct Professor in the Department of Biochemistry

Contact Information

  • Email Address: hashim.al.hashimi@duke.edu

Education

  • Ph.D. Yale University, 2000

Awards, Honors, and Distinctions

  • NAS Award in Molecular Biology. National Academy of Sciences. 2020

Courses Taught

  • BIOCHEM 393: Research Independent Study
  • BIOCHEM 593: Research Independent Study
  • BIOCHEM 695: Understanding NMR Spectroscopy
  • BIOCHEM 700: Graduate Training Internship

In the News

Representative Publications

  • Geng, A; Ganser, L; Roy, R; Shi, H; Pratihar, S; Case, DA; Al-Hashimi, HM, An RNA excited conformational state at atomic resolution., Nature Communications, vol 14 no. 1 (2023) [10.1038/s41467-023-43673-6] [abs].
  • Roy, R; Geng, A; Shi, H; Merriman, DK; Dethoff, EA; Salmon, L; Al-Hashimi, HM, Kinetic Resolution of the Atomic 3D Structures Formed by Ground and Excited Conformational States in an RNA Dynamic Ensemble., J Am Chem Soc, vol 145 no. 42 (2023), pp. 22964-22978 [10.1021/jacs.3c04614] [abs].
  • Gu, S; Szymanski, ES; Rangadurai, AK; Shi, H; Liu, B; Manghrani, A; Al-Hashimi, HM, Dynamic basis for dA•dGTP and dA•d8OGTP misincorporation via Hoogsteen base pairs., Nature Chemical Biology, vol 19 no. 7 (2023), pp. 900-910 [10.1038/s41589-023-01306-5] [abs].
  • Al-Hashimi, HM, Turing, von Neumann, and the computational architecture of biological machines., Proc Natl Acad Sci U S A, vol 120 no. 25 (2023) [10.1073/pnas.2220022120] [abs].
  • Ken, ML; Roy, R; Geng, A; Ganser, LR; Manghrani, A; Cullen, BR; Schulze-Gahmen, U; Herschlag, D; Al-Hashimi, HM, Author Correction: RNA conformational propensities determine cellular activity., Nature, vol 618 no. 7967 (2023) [10.1038/s41586-023-06286-z] [abs].