Geoffrey Steven Ginsburg

Adjunct Professor in the Department of Medicine
Appointments and Affiliations
- Adjunct Professor in the Department of Medicine
- Professor in Pathology
- Professor of Biostatistics and Bioinformatics
- Professor in the School of Nursing
- Member of the Duke Cancer Institute
Contact Information
- Office Location: 101 Science Dr, Rm 2111, CIEMAS Bldg, Durham, NC 27708
- Office Phone: (919) 668-6210
- Websites:
Education
- Children's Hospital Boston, 1990
- Beth Israel Deaconess Medical Center, 1990
- Beth Israel Deaconess Medical Center, 1987
- Ph.D. Boston University, 1984
- M.D. Boston University, 1984
Courses Taught
- BME 493: Projects in Biomedical Engineering (GE)
In the News
- A Combination of Family History and Genomic Screening Provides Best Method of Assessing Cancer Risk (Mar 16, 2021 | Precision Medicine)
- Early Detection of COVID-19: How Your Smartwatch Could Help (Aug 25, 2020 | Duke Magnify)
- A Crystal Ball for the Decade Ahead (Jan 9, 2020)
- Hungry for Innovation: How a MEDx Dinner Led to a Newly Patented Medical Tool (Aug 21, 2019 | Pratt School of Engineering)
- Fecal Matters: Learning About Health Through Waste (Jan 10, 2019 | Pratt School of Engineering)
- Medical Researchers Receive $20 Million in Grants for Genomic Medicine and Breast Cancer Research (Nov 1, 2018 | Duke Health News)
- Proteins in Your Runny Nose Could Reveal a Viral Infection (Feb 22, 2017 | Duke Health News)
- Time to Focus on Your Family Health History (Dec 15, 2015)
- Dr. Geoffrey Ginsburg: The evolution of precision medicine (Oct 21, 2015 | U.S. News & World Report)
- Diagnostic developers target antibiotic resistance (Oct 20, 2015 | Nature)
- Bacterial or Viral? Diagnostic Tool May Help Doctors Track Infection Source (Oct 11, 2015)
- Ginsburg Named Director of School of Medicine-Pratt School Partnership (Aug 10, 2015)
- A fruit billionaire tries to rewrite the textbook on medicine (Jun 20, 2014 | Newsweek)
- Duke Announces Reorganization of Genome Sciences (Mar 24, 2014)
- Blood test can determine whether illness is caused by virus or bacteria (Sep 19, 2013 | CBS News, AP)
- Genomic Test Accurately Sorts Viral vs. Bacterial Infections (Sep 18, 2013)
- Is Aspirin Therapy for You? (Jul 7, 2013)
Representative Publications
- Manolio, TA; Abramowicz, M; Al-Mulla, F; Anderson, W; Balling, R; Berger, AC; Bleyl, S; Chakravarti, A; Chantratita, W; Chisholm, RL; Dissanayake, VHW; Dunn, M; Dzau, VJ; Han, B-G; Hubbard, T; Kolbe, A; Korf, B; Kubo, M; Lasko, P; Leego, E; Mahasirimongkol, S; Majumdar, PP; Matthijs, G; McLeod, HL; Metspalu, A; Meulien, P; Miyano, S; Naparstek, Y; O'Rourke, PP; Patrinos, GP; Rehm, HL; Relling, MV; Rennert, G; Rodriguez, LL; Roden, DM; Shuldiner, AR; Sinha, S; Tan, P; Ulfendahl, M; Ward, R; Williams, MS; Wong, JEL; Green, ED; Ginsburg, GS, Global implementation of genomic medicine: We are not alone., Sci Transl Med, vol 7 no. 290 (2015) [10.1126/scitranslmed.aab0194] [abs].
- Dzau, VJ; Ginsburg, GS; Van Nuys, K; Agus, D; Goldman, D, Aligning incentives to fulfil the promise of personalised medicine., Lancet, vol 385 no. 9982 (2015), pp. 2118-2119 [10.1016/S0140-6736(15)60722-X] [abs].
- Benjamin, AM; Nichols, M; Burke, TW; Ginsburg, GS; Lucas, JE, Comparing reference-based RNA-Seq mapping methods for non-human primate data., Bmc Genomics, vol 15 no. 1 (2014) [10.1186/1471-2164-15-570] [abs].
- Kraft, BD; Piantadosi, CA; Benjamin, AM; Lucas, JE; Zaas, AK; Betancourt-Quiroz, M; Woods, CW; Chang, AL; Roggli, VL; Marshall, CD; Ginsburg, GS; Welty-Wolf, K, Development of a novel preclinical model of pneumococcal pneumonia in nonhuman primates., Am J Respir Cell Mol Biol, vol 50 no. 5 (2014), pp. 995-1004 [10.1165/rcmb.2013-0340OC] [abs].
- Ngo, HT; Wang, H-N; Burke, T; Ginsburg, GS; Vo-Dinh, T, Multiplex detection of disease biomarkers using SERS molecular sentinel-on-chip., Anal Bioanal Chem, vol 406 no. 14 (2014), pp. 3335-3344 [10.1007/s00216-014-7648-4] [abs].
- Power, A; Berger, AC; Ginsburg, GS, Genomics-enabled drug repositioning and repurposing: insights from an IOM Roundtable activity., Jama, vol 311 no. 20 (2014), pp. 2063-2064 [10.1001/jama.2014.3002] [abs].
- Ginsburg, G, Medical genomics: Gather and use genetic data in health care., Nature, vol 508 no. 7497 (2014), pp. 451-453 [10.1038/508451a] [abs].
- Tsalik, EL; Langley, RJ; Dinwiddie, DL; Miller, NA; Yoo, B; van Velkinburgh, JC; Smith, LD; Thiffault, I; Jaehne, AK; Valente, AM; Henao, R; Yuan, X; Glickman, SW; Rice, BJ; McClain, MT; Carin, L; Corey, GR; Ginsburg, GS; Cairns, CB; Otero, RM; Fowler, VG; Rivers, EP; Woods, CW; Kingsmore, SF, An integrated transcriptome and expressed variant analysis of sepsis survival and death., Genome Medicine, vol 6 no. 11 (2014) [10.1186/s13073-014-0111-5] [abs].
- Voora, D; Cyr, D; Lucas, J; Chi, J-T; Dungan, J; McCaffrey, TA; Katz, R; Newby, LK; Kraus, WE; Becker, RC; Ortel, TL; Ginsburg, GS, Aspirin exposure reveals novel genes associated with platelet function and cardiovascular events., J Am Coll Cardiol, vol 62 no. 14 (2013), pp. 1267-1276 [10.1016/j.jacc.2013.05.073] [abs].
- Zaas, AK; Burke, T; Chen, M; McClain, M; Nicholson, B; Veldman, T; Tsalik, EL; Fowler, V; Rivers, EP; Otero, R; Kingsmore, SF; Voora, D; Lucas, J; Hero, AO; Carin, L; Woods, CW; Ginsburg, GS, A host-based RT-PCR gene expression signature to identify acute respiratory viral infection., Sci Transl Med, vol 5 no. 203 (2013) [10.1126/scitranslmed.3006280] [abs].
- Langley, RJ; Tsalik, EL; van Velkinburgh, JC; Glickman, SW; Rice, BJ; Wang, C; Chen, B; Carin, L; Suarez, A; Mohney, RP; Freeman, DH; Wang, M; You, J; Wulff, J; Thompson, JW; Moseley, MA; Reisinger, S; Edmonds, BT; Grinnell, B; Nelson, DR; Dinwiddie, DL; Miller, NA; Saunders, CJ; Soden, SS; Rogers, AJ; Gazourian, L; Fredenburgh, LE; Massaro, AF; Baron, RM; Choi, AMK; Corey, GR; Ginsburg, GS; Cairns, CB; Otero, RM; Fowler, VG; Rivers, EP; Woods, CW; Kingsmore, SF, An integrated clinico-metabolomic model improves prediction of death in sepsis., Sci Transl Med, vol 5 no. 195 (2013) [10.1126/scitranslmed.3005893] [abs].
- Wang, H-N; Fales, AM; Zaas, AK; Woods, CW; Burke, T; Ginsburg, GS; Vo-Dinh, T, Surface-enhanced Raman scattering molecular sentinel nanoprobes for viral infection diagnostics., Anal Chim Acta, vol 786 (2013), pp. 153-158 [10.1016/j.aca.2013.05.017] [abs].
- Ginsburg, GS, Realizing the opportunities of genomics in health care., Jama, vol 309 no. 14 (2013), pp. 1463-1464 [10.1001/jama.2013.1465] [abs].
- Khoury, MJ; Lam, TK; Ioannidis, JPA; Hartge, P; Spitz, MR; Buring, JE; Chanock, SJ; Croyle, RT; Goddard, KA; Ginsburg, GS; Herceg, Z; Hiatt, RA; Hoover, RN; Hunter, DJ; Kramer, BS; Lauer, MS; Meyerhardt, JA; Olopade, OI; Palmer, JR; Sellers, TA; Seminara, D; Ransohoff, DF; Rebbeck, TR; Tourassi, G; Winn, DM; Zauber, A; Schully, SD, Transforming epidemiology for 21st century medicine and public health., Cancer Epidemiol Biomarkers Prev, vol 22 no. 4 (2013), pp. 508-516 [10.1158/1055-9965.EPI-13-0146] [abs].
- Henao, R; Murray, J; Ginsburg, G; Carin, L; Lucas, JE, Patient clustering with uncoded text in electronic medical records., Amia ... Annual Symposium Proceedings. Amia Symposium, vol 2013 (2013), pp. 592-599 [abs].
- Orlando, LA; Buchanan, AH; Hahn, SE; Christianson, CA; Powell, KP; Skinner, CS; Chesnut, B; Blach, C; Due, B; Ginsburg, GS; Henrich, VC, Development and validation of a primary care-based family health history and decision support program (MeTree)., North Carolina Medical Journal, vol 74 no. 4 (2013), pp. 287-296 [abs].
- Ginsburg, GS; Kuderer, NM, Comparative effectiveness research, genomics-enabled personalized medicine, and rapid learning health care: a common bond., Journal of Clinical Oncology, vol 30 no. 34 (2012), pp. 4233-4242 [10.1200/JCO.2012.42.6114] [abs].
- Zarco, MF; Vess, TJ; Ginsburg, GS, The oral microbiome in health and disease and the potential impact on personalized dental medicine., Oral Dis, vol 18 no. 2 (2012), pp. 109-120 [10.1111/j.1601-0825.2011.01851.x] [abs].
- Orlando, LA; Hauser, ER; Christianson, C; Powell, KP; Buchanan, AH; Chesnut, B; Agbaje, AB; Henrich, VC; Ginsburg, G, Protocol for implementation of family health history collection and decision support into primary care using a computerized family health history system., Bmc Health Services Research, vol 11 (2011) [10.1186/1472-6963-11-264] [abs].
- Ginsburg, GS; Staples, J; Abernethy, AP, Academic medical centers: ripe for rapid-learning personalized health care., Sci Transl Med, vol 3 no. 101 (2011) [10.1126/scitranslmed.3002386] [abs].
- Chen, M; Zaas, A; Woods, C; Ginsburg, GS; Lucas, J; Dunson, D; Carin, L, Predicting Viral Infection From High-Dimensional Biomarker Trajectories., Journal of the American Statistical Association, vol 106 no. 496 (2011), pp. 1259-1279 [10.1198/jasa.2011.ap10611] [abs].
- Chan, IS; Ginsburg, GS, Personalized medicine: progress and promise., Annu Rev Genomics Hum Genet, vol 12 (2011), pp. 217-244 [10.1146/annurev-genom-082410-101446] [abs].
- Altshuler, JS; Balogh, E; Barker, AD; Eck, SL; Friend, SH; Ginsburg, GS; Herbst, RS; Nass, SJ; Streeter, CM; Wagner, JA, Opening up to precompetitive collaboration., Sci Transl Med, vol 2 no. 52 (2010) [10.1126/scitranslmed.3001515] [abs].
- Ginsburg, GS, Regression of atherosclerosis with therapeutic antibodies pipe cleaner or pipe dream?, J Am Coll Cardiol, vol 50 no. 24 (2007), pp. 2319-2321 [10.1016/j.jacc.2007.08.039] [abs].
- Lugogo, NL; Ginsburg, GS; Que, LG, Genetic profiling and tailored therapy in asthma: are we there yet?, Current Opinion in Molecular Therapeutics, vol 9 no. 6 (2007), pp. 528-537 [abs].
- Ginsburg, GS; Shah, SH; McCarthy, JJ, Taking cardiovascular genetic association studies to the next level., J Am Coll Cardiol, vol 50 no. 10 (2007), pp. 930-932 [10.1016/j.jacc.2007.05.025] [abs].
- Parker, A; Izmailova, ES; Narang, J; Badola, S; Le, T; Roubenoff, R; Ginsburg, GS; Maier, A; Coblyn, JS; Shadick, NA; Weinblatt, ME, Peripheral blood expression of nuclear factor-kappab-regulated genes is associated with rheumatoid arthritis disease activity and responds differentially to anti-tumor necrosis factor-alpha versus methotrexate., The Journal of Rheumatology, vol 34 no. 9 (2007), pp. 1817-1822 [abs].
- Dressman, HK; Muramoto, GG; Chao, NJ; Meadows, S; Marshall, D; Ginsburg, GS; Nevins, JR; Chute, JP, Gene expression signatures that predict radiation exposure in mice and humans., Plos Medicine, vol 4 no. 4 (2007) [10.1371/journal.pmed.0040106] [abs].
- Dressman, HK; Berchuck, A; Chan, G; Zhai, J; Bild, A; Sayer, R; Cragun, J; Clarke, J; Whitaker, RS; Li, L; Gray, J; Marks, J; Ginsburg, GS; Potti, A; West, M; Nevins, JR; Lancaster, JM, An integrated genomic-based approach to individualized treatment of patients with advanced-stage ovarian cancer., Journal of Clinical Oncology, vol 25 no. 5 (2007), pp. 517-525 [10.1200/JCO.2006.06.3743] [abs].
- Potti, A; Dressman, HK; Bild, A; Riedel, RF; Chan, G; Sayer, R; Cragun, J; Cottrill, H; Kelley, MJ; Petersen, R; Harpole, D; Marks, J; Berchuck, A; Ginsburg, GS; Febbo, P; Lancaster, J; Nevins, JR, Genomic signatures to guide the use of chemotherapeutics., Nature Medicine, vol 12 no. 11 (2006), pp. 1294-1300 [10.1038/nm1491] [abs].
- Ginsburg, GS; Seo, D; Frazier, C, Microarrays coming of age in cardiovascular medicine: standards, predictions, and biology., J Am Coll Cardiol, vol 48 no. 8 (2006), pp. 1618-1620 [10.1016/j.jacc.2006.07.025] [abs].
- Ginsburg, GS; Angrist, M; Cook-Deegan, R, Public health. Genomics and medicine at a crossroads in Chernobyl., Science, vol 314 no. 5796 (2006), pp. 62-63 [10.1126/science.1130274] [abs].
- Stallings, SC; Huse, D; Finkelstein, SN; Crown, WH; Witt, WP; Maguire, J; Hiller, AJ; Sinskey, AJ; Ginsburg, GS, A framework to evaluate the economic impact of pharmacogenomics., Pharmacogenomics, vol 7 no. 6 (2006), pp. 853-862 [10.2217/14622416.7.6.853] [abs].
- Potti, A; Mukherjee, S; Petersen, R; Dressman, HK; Bild, A; Koontz, J; Kratzke, R; Watson, MA; Kelley, M; Ginsburg, GS; West, M; Harpole, DH; Nevins, JR, A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer., The New England Journal of Medicine, vol 355 no. 6 (2006), pp. 570-580 [10.1056/NEJMoa060467] [abs].
- Seo, D; Ginsburg, GS; Goldschmidt-Clermont, PJ, Gene expression analysis of cardiovascular diseases: novel insights into biology and clinical applications., J Am Coll Cardiol, vol 48 no. 2 (2006), pp. 227-235 [10.1016/j.jacc.2006.02.070] [abs].
- Haga, SB; Ginsburg, GS, Prescribing BiDil: is it black and white?, J Am Coll Cardiol, vol 48 no. 1 (2006), pp. 12-14 [10.1016/j.jacc.2006.04.017] [abs].
- Cotten, CM; Ginsburg, GS; Goldberg, RN; Speer, MC, Genomic analyses: a neonatology perspective., The Journal of Pediatrics, vol 148 no. 6 (2006), pp. 720-726 [10.1016/j.jpeds.2006.01.006] [abs].
- West, M; Ginsburg, GS; Huang, AT; Nevins, JR, Embracing the complexity of genomic data for personalized medicine., Genome Research, vol 16 no. 5 (2006), pp. 559-566 [10.1101/gr.3851306] [abs].
- Ginsburg, GS; Haga, SB, Translating genomic biomarkers into clinically useful diagnostics., Expert Rev Mol Diagn, vol 6 no. 2 (2006), pp. 179-191 [10.1586/14737159.6.2.179] [abs].
- Ginsburg, GS; Konstance, RP; Allsbrook, JS; Schulman, KA, Implications of pharmacogenomics for drug development and clinical practice., Archives of Internal Medicine, vol 165 no. 20 (2005), pp. 2331-2336 [10.1001/archinte.165.20.2331] [abs].
- Ginsburg, GS; Donahue, MP; Newby, LK, Prospects for personalized cardiovascular medicine: the impact of genomics., J Am Coll Cardiol, vol 46 no. 9 (2005), pp. 1615-1627 [10.1016/j.jacc.2005.06.075] [abs].
- Willard, HF; Angrist, M; Ginsburg, GS, Genomic medicine: genetic variation and its impact on the future of health care., Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences, vol 360 no. 1460 (2005), pp. 1543-1550 [10.1098/rstb.2005.1683] [abs].
- Seo, D; Ginsburg, GS, Genomic medicine: bringing biomarkers to clinical medicine., Current Opinion in Chemical Biology, vol 9 no. 4 (2005), pp. 381-386 [10.1016/j.cbpa.2005.06.009] [abs].
- Abrahams, E; Ginsburg, GS; Silver, M, The Personalized Medicine Coalition: goals and strategies., American Journal of Pharmacogenomics : Genomics Related Research in Drug Development and Clinical Practice, vol 5 no. 6 (2005), pp. 345-355 [10.2165/00129785-200505060-00002] [abs].
- Ross, JS; Schenkein, DP; Pietrusko, R; Rolfe, M; Linette, GP; Stec, J; Stagliano, NE; Ginsburg, GS; Symmans, WF; Pusztai, L; Hortobagyi, GN, Targeted therapies for cancer 2004., American Journal of Clinical Pathology, vol 122 no. 4 (2004), pp. 598-609 [10.1309/5CWP-U41A-FR1V-YM3F] [abs].
- Ross, JS; Ginsburg, GS, Integration of molecular diagnostics with therapeutics: implications for drug discovery and patient care., Expert Review of Molecular Diagnostics, vol 2 no. 6 (2002), pp. 531-541 [10.1586/14737159.2.6.531] [abs].
- Meyer, JM; Ginsburg, GS, The path to personalized medicine., Current Opinion in Chemical Biology, vol 6 no. 4 (2002), pp. 434-438 [10.1016/s1367-5931(02)00340-x] [abs].
- Ginsburg, GS; McCarthy, JJ, Personalized medicine: revolutionizing drug discovery and patient care., Trends in Biotechnology, vol 19 no. 12 (2001), pp. 491-496 [10.1016/s0167-7799(01)01814-5] [abs].