David Stephen Pisetsky

David Stephen Pisetsky

Professor of Medicine

Studies in my laboratory concern the immunological properties of DNA as related to two main topics: 1) the induction of anti-DNA responses in systemic lupus erythematosus; and 2) the stimulation of innate immunity by bacterial DNA. These topics are closely linked since we have established novel disease models in which lupus-like illness can be induced in normal mice by bacterial DNA under conditions in which mammalian DNA is inactive. This model has been useful in elucidating mechanisms of DNA antigen drive in autoimmunity.

To pursue these studies, our laboratory conducts investigations in the following areas: 1) specificity of anti-DNA for epitopes on mammalian and bacterial DNA; 2) molecular analysis of murine mononclonal anti-DNA antibodies; 3) histopathological analyses of DNA-immunized mice; 4) in vitro analysis of proliferation, antibody production and cytokine expression in human and murine immune cells; and 5) analysis of DNA binding to cell surface molecules on B cells, T cells and macrophages. Results of these studies have allowed identification of at least two structural motifs that are immunoactive. We are also exploring the impact of chemical modifications of the DNA backbone.

In addition to work on the immunology of DNA, I am also involved in clinical trials related to new immunomodulatory agents in the treatment of rheumatoid arthritis as well as serological markers of disease activity.

The areas of research for which I am known nationally are anti-DNA antibodies, systemic lupus erythematosus and immunological properties of DNA. I have written textbook chapters and reviews on all these subjects.

Appointments and Affiliations

  • Professor of Medicine
  • Professor of Immunology
  • Member of the Duke Cancer Institute
  • Member of the Duke Human Vaccine Institute

Contact Information

  • Office Location: VA Med Ctr, 508 Fulton St, Durham, NC 27705
  • Office Phone: (919) 286-6835
  • Email Address: david.pisetsky@duke.edu

Education

  • Yale University School of Medicine, 1974
  • Yale University School of Medicine, 1974
  • M.D. Yeshiva University, Albert Einstein College of Medicine, 1973
  • Ph.D. Yeshiva University, Albert Einstein College of Medicine, 1972

Courses Taught

  • IMMUNOL 493: Research Independent Study
  • IMMUNOL 494: Research Independent Study

In the News

Representative Publications

  • Pisetsky, DS; Spencer, DM; Rovin, B; Lipsky, PE, Role of ANA testing in the classification of patients with systemic lupus erythematosus., Ann Rheum Dis, vol 80 no. 8 (2021) [10.1136/annrheumdis-2019-216259] [abs].
  • Toes, R; Pisetsky, DS, Response to: "How to communicate in science" by Klareskog et al., Ann Rheum Dis, vol 79 no. 12 (2020) [10.1136/annrheumdis-2019-216045] [abs].
  • Toes, R; Pisetsky, DS, Response to: 'Comment on editorial 'Pathogenic effector functions of ACPA: where do we stand'' by Holmdahl., Ann Rheum Dis, vol 79 no. 10 (2020) [10.1136/annrheumdis-2019-215870] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, BH, Response to 'Antinuclear antibodies by indirect immunofluorescence and solid phase assays' by Bossuyt et al., Ann Rheum Dis, vol 79 no. 6 (2020) [10.1136/annrheumdis-2019-215479] [abs].
  • Pisetsky, DS, Evolving story of autoantibodies in systemic lupus erythematosus., J Autoimmun, vol 110 (2020) [10.1016/j.jaut.2019.102356] [abs].
  • Pisetsky, DS; Spencer, DM; Mobarrez, F; Fuzzi, E; Gunnarsson, I; Svenungsson, E, The binding of SLE autoantibodies to mitochondria., Clin Immunol, vol 212 (2020) [10.1016/j.clim.2020.108349] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, B, Response to: "Antinuclear autoantibodies: discordance among four different assays" by Pacheco et al., Ann Rheum Dis, vol 79 no. 1 (2020) [10.1136/annrheumdis-2018-214766] [abs].
  • Pisetsky, DS; Bossuyt, X; Meroni, PL, ANA as an entry criterion for the classification of SLE., Autoimmun Rev, vol 18 no. 12 (2019) [10.1016/j.autrev.2019.102400] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, BH, Response to: 'Antinuclear antibody as entry criterion for classification of systemic lupus erythematosus: pitfalls and opportunities' by Bossuyt et al., Ann Rheum Dis, vol 78 no. 8 (2019) [10.1136/annrheumdis-2018-213841] [abs].
  • Mobarrez, F; Fuzzi, E; Gunnarsson, I; Larsson, A; Eketjäll, S; Pisetsky, DS; Svenungsson, E, Microparticles in the blood of patients with SLE: Size, content of mitochondria and role in circulating immune complexes., J Autoimmun, vol 102 (2019), pp. 142-149 [10.1016/j.jaut.2019.05.003] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, BH, Response to: 'Pitfalls of antinuclear antibody detection in systemic lupus erythematosus: the positive experience of a national multi-center study' by Pregnalato et al., Ann Rheum Dis, vol 78 no. 6 (2019) [10.1136/annrheumdis-2018-213582] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, BH, Response to: 'Variation in antinuclear antibody detection by automated indirect immunofluorescence analysis' by van Hoovels et al., Ann Rheum Dis, vol 78 no. 6 (2019) [10.1136/annrheumdis-2018-213558] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, BH, Response to: 'Unending story of the indirect immunofluorescence assay on HEp-2 cells: old problems and new solutions?' by Meroni et al., Ann Rheum Dis, vol 78 no. 6 (2019) [10.1136/annrheumdis-2018-213537] [abs].
  • Pisetsky, DS, Unexpected link between mitochondrial DNA and T cell help in systemic lupus erythematosus., Ann Rheum Dis, vol 78 no. 6 (2019) [10.1136/annrheumdis-2019-215597] [abs].
  • Pisetsky, DS; Lipsky, PE, Role of Antinuclear Antibody Determinations in Classification Criteria for Systemic Lupus Erythematosus: Comment on the Article by Leuchten et al., Arthritis Care Res (Hoboken), vol 71 no. 5 (2019) [10.1002/acr.23559] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, BH, Response to: 'Lack of standardization of ANA and implications for drug development and precision medicine' by Mahler., Ann Rheum Dis, vol 78 no. 5 (2019) [10.1136/annrheumdis-2018-213399] [abs].
  • Mobarrez, F; Svenungsson, E; Pisetsky, DS, Microparticles as autoantigens in systemic lupus erythematosus., Eur J Clin Invest, vol 48 no. 12 (2018) [10.1111/eci.13010] [abs].
  • Putterman, C; Pisetsky, DS; Petri, M; Caricchio, R; Wu, AHB; Sanz, I; Oates, JC; Wallace, S; Sorek, R; Gerwien, R; Safer, P; Jakobi-Brook, K; Cohen, IR, The SLE-key test serological signature: new insights into the course of lupus., Rheumatology (Oxford), vol 57 no. 9 (2018), pp. 1632-1640 [10.1093/rheumatology/key149] [abs].
  • Pisetsky, DS, Role of Epstein-Barr virus infection in SLE: gene-environment interactions at the molecular level., Ann Rheum Dis, vol 77 no. 9 (2018), pp. 1249-1250 [10.1136/annrheumdis-2018-213783] [abs].
  • Pisetsky, DS; Spencer, DM; Lipsky, PE; Rovin, BH, Assay variation in the detection of antinuclear antibodies in the sera of patients with established SLE., Ann Rheum Dis, vol 77 no. 6 (2018), pp. 911-913 [10.1136/annrheumdis-2017-212599] [abs].
  • Pisetsky, DS, Effects of immune checkpoint inhibitors on B cells: relationship to immune-related adverse events., Ann Rheum Dis, vol 77 no. 6 (2018), pp. 795-796 [10.1136/annrheumdis-2018-213561] [abs].
  • Pisetsky, DS, How the gut inflames the joints., Ann Rheum Dis, vol 77 no. 5 (2018), pp. 634-635 [10.1136/annrheumdis-2018-212942] [abs].
  • Naqvi, I; Gunaratne, R; McDade, JE; Moreno, A; Rempel, RE; Rouse, DC; Herrera, SG; Pisetsky, DS; Lee, J; White, RR; Sullenger, BA, Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis., Molecular Therapy : the Journal of the American Society of Gene Therapy, vol 26 no. 4 (2018), pp. 1020-1031 [10.1016/j.ymthe.2018.02.018] [abs].
  • Spencer, DM; Dye, JR; Piantadosi, CA; Pisetsky, DS, The release of microparticles and mitochondria from RAW 264.7 murine macrophage cells undergoing necroptotic cell death in vitro., Exp Cell Res, vol 363 no. 2 (2018), pp. 151-159 [10.1016/j.yexcr.2017.12.024] [abs].
  • Frank-Bertoncelj, M; Pisetsky, DS; Kolling, C; Michel, BA; Gay, RE; Jüngel, A; Gay, S, TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles., Frontiers in Immunology, vol 9 (2018) [10.3389/fimmu.2018.00028] [abs].
  • Pisetsky, DS, The biological functions of DNA: from the sublime to the slime., Arthritis Research & Therapy, vol 19 no. 1 (2017) [10.1186/s13075-017-1464-0] [abs].
  • Zerwas, S; Larsen, JT; Petersen, L; Thornton, LM; Quaranta, M; Koch, SV; Pisetsky, D; Mortensen, PB; Bulik, CM, Eating Disorders, Autoimmune, and Autoinflammatory Disease., Pediatrics, vol 140 no. 6 (2017) [10.1542/peds.2016-2089] [abs].
  • Pisetsky, DS, Advances in the Treatment of Rheumatoid Arthritis: Costs and Challenges., North Carolina Medical Journal, vol 78 no. 5 (2017), pp. 337-340 [10.18043/ncm.78.5.337] [abs].
  • Pisetsky, DS, Antinuclear antibody testing - misunderstood or misbegotten?, Nat Rev Rheumatol, vol 13 no. 8 (2017), pp. 495-502 [10.1038/nrrheum.2017.74] [abs].
  • Pisetsky, DS, EULAR recommendations for disease management: guidance not guidelines., Ann Rheum Dis, vol 76 no. 6 (2017), pp. 935-938 [10.1136/annrheumdis-2016-211005] [abs].
  • Pisetsky, DS; Rovin, BH; Lipsky, PE, New Perspectives in Rheumatology: Biomarkers as Entry Criteria for Clinical Trials of New Therapies for Systemic Lupus Erythematosus: The Example of Antinuclear Antibodies and Anti-DNA., Arthritis Rheumatol, vol 69 no. 3 (2017), pp. 487-493 [10.1002/art.40008] [abs].
  • Pisetsky, DS, Mechanisms of Chromatin Remodeling and Repurposing During Extracellular Translocation., Advances in Protein Chemistry and Structural Biology, vol 106 (2017), pp. 113-137 [10.1016/bs.apcsb.2016.08.003] [abs].
  • Mobarrez, F; Abraham-Nordling, M; Aguilera-Gatica, K; Friberg, I; Antovic, A; Pisetsky, DS; Jörneskog, G; Wallen, H, The expression of microvesicles in the blood of patients with Graves' disease and its relationship to treatment., Clin Endocrinol (Oxf), vol 84 no. 5 (2016), pp. 729-735 [10.1111/cen.12872] [abs].
  • Magna, M; Pisetsky, DS, The Alarmin Properties of DNA and DNA-associated Nuclear Proteins., Clinical Therapeutics, vol 38 no. 5 (2016), pp. 1029-1041 [10.1016/j.clinthera.2016.02.029] [abs].
  • Stearns, NA; Pisetsky, DS, The role of monogamous bivalency and Fc interactions in the binding of anti-DNA antibodies to DNA antigen., Clin Immunol, vol 166-167 (2016), pp. 38-47 [10.1016/j.clim.2016.04.004] [abs].
  • Sokolove, J; Pisetsky, D, Bone loss, pain and inflammation: three faces of ACPA in RA pathogenesis., Ann Rheum Dis, vol 75 no. 4 (2016), pp. 637-639 [10.1136/annrheumdis-2015-208308] [abs].
  • Pisetsky, DS, Anti-DNA antibodies--quintessential biomarkers of SLE., Nat Rev Rheumatol, vol 12 no. 2 (2016), pp. 102-110 [10.1038/nrrheum.2015.151] [abs].
  • Wang, J; Lon, H-K; Lee, S-L; Burckart, GJ; Pisetsky, DS, Oligonucleotide-Based Drug Development: Considerations for Clinical Pharmacology and Immunogenicity., Therapeutic Innovation & Regulatory Science, vol 49 no. 6 (2015), pp. 861-868 [10.1177/2168479015592195] [abs].
  • Magna, M; Pisetsky, DS, The Role of Cell Death in the Pathogenesis of SLE: Is Pyroptosis the Missing Link?, Scand J Immunol, vol 82 no. 3 (2015), pp. 218-224 [10.1111/sji.12335] [abs].
  • Pisetsky, DS, Rheumatoid vasculitis: going, going, but not yet gone., Arthritis Research & Therapy, vol 17 (2015) [10.1186/s13075-015-0635-0] [abs].
  • Mobarrez, F; Sjövik, C; Soop, A; Hållström, L; Frostell, C; Pisetsky, DS; Wallén, H, CD40L expression in plasma of volunteers following LPS administration: A comparison between assay of CD40L on platelet microvesicles and soluble CD40L., Platelets, vol 26 no. 5 (2015), pp. 486-490 [10.3109/09537104.2014.932339] [abs].
  • Leuchten, N; Bauernfeind, B; Kuttner, J; Stamm, T; Smolen, JS; Pisetsky, DS; Aringer, M, Relevant concepts of functioning for patients with systemic lupus erythematosus identified in a Delphi exercise of experts and a literature review., Arthritis Care Res (Hoboken), vol 66 no. 12 (2014), pp. 1895-1904 [10.1002/acr.22372] [abs].
  • Pisetsky, DS, The complex role of DNA, histones and HMGB1 in the pathogenesis of SLE., Autoimmunity, vol 47 no. 8 (2014), pp. 487-493 [10.3109/08916934.2014.921811] [abs].
  • Grossman, JM; Clowse, MEB; Izmirly, PM; Kamen, DL; Levine, AK; Mackey, M; McCune, WJ; McGwin, J; Pisetsky, DS; Utset, T; Yazdany, J, Hydroxychloroquine Dosing and Disease Activity in a Large Multi-Racial Lupus Cohort, Arthritis & Rheumatology, vol 66 (2014), pp. S296-S297 [abs].
  • Ullal, AJ; Marion, TN; Pisetsky, DS, The role of antigen specificity in the binding of murine monoclonal anti-DNA antibodies to microparticles from apoptotic cells., Clin Immunol, vol 154 no. 2 (2014), pp. 178-187 [10.1016/j.clim.2014.05.007] [abs].
  • Pisetsky, DS; Trace, SE; Brownley, KA; Hamer, RM; Zucker, NL; Roux-Lombard, P; Dayer, J-M; Bulik, CM, The expression of cytokines and chemokines in the blood of patients with severe weight loss from anorexia nervosa: an exploratory study., Cytokine, vol 69 no. 1 (2014), pp. 110-115 [10.1016/j.cyto.2014.05.018] [abs].
  • Spencer, DM; Mobarrez, F; Wallén, H; Pisetsky, DS, The expression of HMGB1 on microparticles from Jurkat and HL-60 cells undergoing apoptosis in vitro., Scand J Immunol, vol 80 no. 2 (2014), pp. 101-110 [10.1111/sji.12191] [abs].
  • Wang, X; Stearns, NA; Li, X; Pisetsky, DS, The effect of polyamines on the binding of anti-DNA antibodies from patients with SLE and normal human subjects., Clin Immunol, vol 153 no. 1 (2014), pp. 94-103 [10.1016/j.clim.2014.04.003] [abs].
  • Pisetsky, DS, The expression of HMGB1 on microparticles released during cell activation and cell death in vitro and in vivo., Mol Med, vol 20 (2014), pp. 158-163 [10.2119/molmed.2014.00014] [abs].
  • Spencer, DM; Gauley, J; Pisetsky, DS, The properties of microparticles from RAW 264.7 macrophage cells undergoing in vitro activation or apoptosis., Innate Immun, vol 20 no. 3 (2014), pp. 239-248 [10.1177/1753425913492552] [abs].
  • Magna, M; Pisetsky, DS, The role of HMGB1 in the pathogenesis of inflammatory and autoimmune diseases., Mol Med, vol 20 (2014), pp. 138-146 [10.2119/molmed.2013.00164] [abs].
  • Pisetsky, DS, Gout, tophi and the wonders of NETs, Arthritis Research & Therapy, vol 16 no. 5 (2014) [abs].
  • Mobarrez, F; Antoniewicz, L; Bosson, JA; Kuhl, J; Pisetsky, DS; Lundbäck, M, The effects of smoking on levels of endothelial progenitor cells and microparticles in the blood of healthy volunteers., Plos One, vol 9 no. 2 (2014) [10.1371/journal.pone.0090314] [abs].
  • Pisetsky, DS, Tumor necrosis factor: is it time to change the name?, Arthritis Research & Therapy, vol 16 no. 2 (2014) [10.1186/ar4541] [abs].
  • Pisetsky, DS, Gout, tophi and the wonders of NETs., Arthritis Research & Therapy, vol 16 no. 5 (2014) [10.1186/s13075-014-0431-2] [abs].
  • Pisetsky, DS, Immune activation by histones: plusses and minuses in inflammation., Eur J Immunol, vol 43 no. 12 (2013), pp. 3163-3166 [10.1002/eji.201344175] [abs].
  • Kim, Y; Trace, SE; Crowley, JJ; Brownley, KA; Hamer, RM; Pisetsky, DS; Sullivan, PF; Bulik, CM, Assessment of gene expression in peripheral blood using RNAseq before and after weight restoration in anorexia nervosa., Psychiatry Research, vol 210 no. 1 (2013), pp. 287-293 [10.1016/j.psychres.2013.05.026] [abs].
  • Pisetsky, DS, The danger of sex and death in Scarf1(-/-) autoimmune mice., Nat Immunol, vol 14 no. 9 (2013), pp. 888-889 [10.1038/ni.2684] [abs].
  • Pisetsky, DS, The Choosing Wisely initiative: does it have your back?, Arthritis Research & Therapy, vol 15 no. 4 (2013) [10.1186/ar4257] [abs].
  • Soop, A; Hållström, L; Frostell, C; Wallén, H; Mobarrez, F; Pisetsky, DS, Effect of lipopolysaccharide administration on the number, phenotype and content of nuclear molecules in blood microparticles of normal human subjects., Scand J Immunol, vol 78 no. 2 (2013), pp. 205-213 [10.1111/sji.12076] [abs].
  • Dye, JR; Ullal, AJ; Pisetsky, DS, The role of microparticles in the pathogenesis of rheumatoid arthritis and systemic lupus erythematosus., Scand J Immunol, vol 78 no. 2 (2013), pp. 140-148 [10.1111/sji.12068] [abs].
  • Pisetsky, DS, The 2013 ACR meeting: mad macs at the Marina., Arthritis Research & Therapy, vol 15 no. 6 (2013) [10.1186/ar4419] [abs].
  • Pisetsky, DS, The effectors of innate immunity: DAMPs, DAMEs, or DIMEs?, Arthritis Research & Therapy, vol 15 no. 5 (2013) [10.1186/ar4363] [abs].
  • Rutledge, HR; Jiang, W; Yang, J; Warg, LA; Schwartz, DA; Pisetsky, DS; Yang, IV, Gene expression profiles of RAW264.7 macrophages stimulated with preparations of LPS differing in isolation and purity., Innate Immun, vol 18 no. 1 (2012), pp. 80-88 [10.1177/1753425910393540] [abs].
  • Distler, JHW; Akhmetshina, A; Dees, C; Jüngel, A; Stürzl, M; Gay, S; Pisetsky, DS; Schett, G; Distler, O, Induction of apoptosis in circulating angiogenic cells by microparticles., Arthritis Rheum, vol 63 no. 7 (2011), pp. 2067-2077 [10.1002/art.30361] [abs].
  • Ullal, AJ; Reich, CF; Clowse, M; Criscione-Schreiber, LG; Tochacek, M; Monestier, M; Pisetsky, DS, Microparticles as antigenic targets of antibodies to DNA and nucleosomes in systemic lupus erythematosus., J Autoimmun, vol 36 no. 3-4 (2011), pp. 173-180 [10.1016/j.jaut.2011.02.001] [abs].
  • Pisetsky, DS; Gauley, J; Ullal, AJ, Microparticles as a source of extracellular DNA., Immunol Res, vol 49 no. 1-3 (2011), pp. 227-234 [10.1007/s12026-010-8184-8] [abs].
  • Pisetsky, DS, Platelet microparticles: making blood a bad humor., The Journal of Rheumatology, vol 38 no. 4 (2011), pp. 590-592 [10.3899/jrheum.101359] [abs].
  • Pisetsky, DS, The role of HMGB1 in efferocytosis: when the dead go unburied. Focus on "HMGB1 inhibits macrophage activity in efferocytosis through binding to the alphavbeta3-integrin"., Am J Physiol Cell Physiol, vol 299 no. 6 (2010), pp. C1253-C1255 [10.1152/ajpcell.00397.2010] [abs].
  • Pisetsky, DS; Ullal, AJ, The blood nucleome in the pathogenesis of SLE., Autoimmun Rev, vol 10 no. 1 (2010), pp. 35-37 [10.1016/j.autrev.2010.07.007] [abs].
  • Pisetsky, DS, Charlie's List., Ann Intern Med, vol 153 no. 5 (2010) [10.7326/0003-4819-153-5-201009070-00012] [abs].
  • Pisetsky, DS; Lipsky, PE, Microparticles as autoadjuvants in the pathogenesis of SLE., Nat Rev Rheumatol, vol 6 no. 6 (2010), pp. 368-372 [10.1038/nrrheum.2010.66] [abs].
  • Gauley, J; Pisetsky, DS, The release of microparticles by RAW 264.7 macrophage cells stimulated with TLR ligands., J Leukoc Biol, vol 87 no. 6 (2010), pp. 1115-1123 [10.1189/jlb.0709465] [abs].
  • Ullal, AJ; Pisetsky, DS, The release of microparticles by Jurkat leukemia T cells treated with staurosporine and related kinase inhibitors to induce apoptosis., Apoptosis, vol 15 no. 5 (2010), pp. 586-596 [10.1007/s10495-010-0470-3] [abs].
  • Pisetsky, DS, HMGB1: a dangerous player in lupus pathogenesis., The Journal of Rheumatology, vol 37 no. 4 (2010), pp. 689-691 [10.3899/jrheum.091459] [abs].
  • Ullal, AJ; Pisetsky, DS; Reich, CF, Use of SYTO 13, a fluorescent dye binding nucleic acids, for the detection of microparticles in in vitro systems., Cytometry A, vol 77 no. 3 (2010), pp. 294-301 [10.1002/cyto.a.20833] [abs].
  • Grundtman, C; Bruton, J; Yamada, T; Ostberg, T; Pisetsky, DS; Harris, HE; Andersson, U; Lundberg, IE; Westerblad, H, Effects of HMGB1 on in vitro responses of isolated muscle fibers and functional aspects in skeletal muscles of idiopathic inflammatory myopathies., Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, vol 24 no. 2 (2010), pp. 570-578 [10.1096/fj.09-144782] [abs].
  • Beyer, C; Pisetsky, DS, The role of microparticles in the pathogenesis of rheumatic diseases., Nat Rev Rheumatol, vol 6 no. 1 (2010), pp. 21-29 [10.1038/nrrheum.2009.229] [abs].
  • Pisetsky, DS; Vrabie, IA, Antibodies to DNA: infection or genetics?, Lupus, vol 18 no. 13 (2009), pp. 1176-1180 [10.1177/0961203309106492] [abs].
  • Su, K-Y; Pisetsky, DS, The role of extracellular DNA in autoimmunity in SLE., Scand J Immunol, vol 70 no. 3 (2009), pp. 175-183 [10.1111/j.1365-3083.2009.02300.x] [abs].
  • Pisetsky, DS; Rönnblom, L, Systemic lupus erythematosus: a matter of life and death., Arthritis and Rheumatism, vol 60 no. 6 (2009), pp. 1567-1570 [10.1002/art.24531] [abs].
  • Gauley, J; Pisetsky, DS, The translocation of HMGB1 during cell activation and cell death., Autoimmunity, vol 42 no. 4 (2009), pp. 299-301 [10.1080/08916930902831522] [abs].
  • Crowley, SD; Vasievich, MP; Ruiz, P; Gould, SK; Parsons, KK; Pazmino, AK; Facemire, C; Chen, BJ; Kim, H-S; Tran, TT; Pisetsky, DS; Barisoni, L; Prieto-Carrasquero, MC; Jeansson, M; Foster, MH; Coffman, TM, Glomerular type 1 angiotensin receptors augment kidney injury and inflammation in murine autoimmune nephritis., J Clin Invest, vol 119 no. 4 (2009), pp. 943-953 [10.1172/JCI34862] [abs].
  • Reich, CF; Pisetsky, DS, The content of DNA and RNA in microparticles released by Jurkat and HL-60 cells undergoing in vitro apoptosis., Exp Cell Res, vol 315 no. 5 (2009), pp. 760-768 [10.1016/j.yexcr.2008.12.014] [abs].
  • Pisetsky, DS, Microparticles as biomarkers in autoimmunity: from dust bin to center stage., Arthritis Research & Therapy, vol 11 no. 6 (2009) [10.1186/ar2856] [abs].