Bastiaan Driehuys

Bastiaan Driehuys

Professor of Radiology

My research program is focused on developing and applying hyperpolarized gases to enable fundamentally new applications in MRI. Currently we use this technology to non-invasively image pulmonary function in 3D. Hyperpolarization involves aligning nuclei to a high degree to enhance their MRI signal by 5-6 orders of magnitude. Thus, despite the low density of gases relative to water (the ordinary signal source in MRI), they can be imaged at high-resolution in a single breath. This technology leads to a host of interesting areas of study including: investigating the basic physics of hyperpolarization, developing new MR methods and hardware for image acquisition, image analysis and quantification, and of, course applying this technology to a host of chronic diseases including, asthma, chronic obstructive pulmonary disease, and pulmonary fibrosis.

Appointments and Affiliations

  • Professor of Radiology
  • Professor of Biomedical Engineering

Contact Information

  • Office Location: 161-B Bryan Research, 311 Research Drive, Durham, NC 27710
  • Office Phone: (919) 684-7786
  • Email Address:
  • Websites:


  • Ph.D. Princeton University, 1995

Courses Taught

  • BME 791: Graduate Independent Study
  • BME 792: Continuation of Graduate Independent Study
  • PHYSICS 493: Research Independent Study
  • PHYSICS 495: Thesis Independent Study

Representative Publications

  • Kaushik, SS; Freeman, MS; Cleveland, ZI; Davies, J; Stiles, J; Virgincar, RS; Robertson, SH; He, M; Kelly, KT; Foster, WM; McAdams, HP; Driehuys, B, Probing the regional distribution of pulmonary gas exchange through single-breath gas- and dissolved-phase 129Xe MR imaging., J Appl Physiol (1985), vol 115 no. 6 (2013), pp. 850-860 [10.1152/japplphysiol.00092.2013] [