Louis Edwin DeFrate
Laszlo Ormandy Distinguished Professor of Orthopaedic Surgery
Appointments and Affiliations
- Laszlo Ormandy Distinguished Professor of Orthopaedic Surgery
- Professor in Orthopaedic Surgery
- Professor in the Department of Biomedical Engineering
- Affiliate of the Duke Regeneration Center
Contact Information
- Office Location: Room 379, Medical Sciences Research Building, Box 3093 Med. Ctr., Durham, NC 27710
- Office Phone: +1 919 681 9959
- Email Address: lou.defrate@duke.edu
- Websites:
Education
- Sc.D. Massachusetts Institute of Technology, 2005
Awards, Honors, and Distinctions
- Kappa Delta Young Investigator Award. American Academy of Orthopaedic Surgeons and the Orthopaedic Research Society. 2016
Courses Taught
- EGR 393: Research Projects in Engineering
- BME 792: Continuation of Graduate Independent Study
- BME 791: Graduate Independent Study
- BME 493: Projects in Biomedical Engineering (GE)
In the News
- Duke Awards 44 Distinguished Professorships (May 4, 2023 | Duke Today)
- Study Shows Men and Women Tear ACL the Same Way In Non-Contact Injury (Apr 18, 2018 | Duke Health News)
- His and Her Knee Injuries Occur the Same Way (Apr 17, 2018 | US News and World Report)
- How to prevent knee injuries (Nov 30, 2017 | KSAT News)
- Knee arthritis in Americans has doubled since 1940 (Aug 16, 2017 | Science Magazine)
- Athletes: Try this to prevent ACL tears and knee injuries (Aug 9, 2017 | WRAL News)
- Clinical Sciences Day: Collaboration, Mentorship Lead to Science Successes (Oct 22, 2013 | Duke Research Blog)
Representative Publications
- Zhao, Q; Holt, A; Spritzer, CE; DeFrate, LE; McNulty, AL; Wang, N, High angular resolution diffusion imaging (HARDI) of porcine menisci: a comparison of diffusion tensor imaging and generalized q-sampling imaging, Quantitative Imaging in Medicine and Surgery, vol 14 no. 4 (2024), pp. 2738-2746 [10.21037/qims-23-1355] [abs].
- Heckelman, LN; Kratzer, AL; Spritzer, CE; Soher, BJ; Lewis, BD; DeFrate, LE, Influence of running on femoroacetabular joint bone-to-bone distances., J Orthop Res, vol 42 no. 4 (2024), pp. 837-842 [10.1002/jor.25735] [abs].
- Coppock, JA; Zimmer, NE; Spritzer, CE; Goode, AP; DeFrate, LE, Automated segmentation and prediction of intervertebral disc morphology and uniaxial deformations from MRI., Osteoarthr Cartil Open, vol 5 no. 3 (2023) [10.1016/j.ocarto.2023.100378] [abs].
- Coppock, JA; McNulty, AL; Porter Starr, KN; Holt, AG; Borack, MS; Kosinski, AS; Collins, AT; Bales, CW; DeFrate, LE, The effects of a 6-month weight loss intervention on physical function and serum biomarkers in older adults with and without osteoarthritis., Osteoarthr Cartil Open, vol 5 no. 3 (2023) [10.1016/j.ocarto.2023.100376] [abs].
- Kim-Wang, SY; Spritzer, CE; Owusu-Akyaw, K; Coppock, JA; Goode, AP; Englander, ZA; Wittstein, JR; DeFrate, LE, The Predicted Position of the Knee Near the Time of ACL Rupture Is Similar Between 2 Commonly Observed Patterns of Bone Bruising on MRI: Response., Am J Sports Med, vol 51 no. 8 (2023), pp. NP22-NP24 [10.1177/03635465231172184] [abs].