MEDx Postdoc Seminar & Lunch

Friday, March 25, 2016 - 12:00pm to 1:30pm
Workshop Room, The Edge, Bostock Library

Computational Modeling of the Heart: Challenges and Open Problems, Simone Rossi, CEE Postdoctoral Fellow

Mathematical and computational modeling of the human heart and its function can expand our understanding of various cardiac diseases, which remain the most common cause of death in the developed world. Like other physiological systems, the heart can be understood as a complex multiscale system involving interacting phenomena at the molecular, cellular, tissue, and organ levels.  With several examples I will illustrate some of the fundamental challenges of developing multiphysics and multiscale models for simulating heart function, such as the upscaling from single-cell models to the entire cardiac muscle and the proper coupling of electrophysiology and tissue mechanics to simulate electromechanical feedback, among many others.