Warren M. Grill
Professor of Biomedical Engineering
Our research employs engineering approaches to understand and control neural function. We work on fundamental questions and applied development in electrical stimulation of the nervous system to restore function to individuals with neurological impairment or injury.
Current projects include:
• understanding the mechanisms of and developing advanced approaches to deep brain stimulation to treat movement disorders,
• developing novel approaches to peripheral nerve electrical stimulation for restoration of bladder function,
• understanding the mechanisms of and developing advanced approaches to spinal cord stimulation to treat chronic pain,
• understanding and controlling the cellular effects of transcranial magnetic stimulation, and
• design of novel electrodes and waveforms for selective stimulation of the nervous system.
Appointments and Affiliations
- Professor of Biomedical Engineering
- Edmund T. Pratt, Jr. School Distinguished Professor of Biomedical Engineering
- Bass Fellow
- Associate of the Duke Initiative for Science & Society
- Professor in Neurobiology
- Professor in Neurosurgery
- Core Faculty in Innovation & Entrepreneurship
- Professor in the Department of Electrical and Computer Engineering
- Faculty Network Member of the Duke Institute for Brain Sciences
- Office Location: CIEMAS 1139, Durham, NC 27708
- Office Phone: (919) 660-5276
- Email Address: firstname.lastname@example.org
- Ph.D. Case Western Reserve University, 1995
- M.S. Case Western Reserve University, 1992
- B.S. Boston University, 1989
Research InterestsNeural engineering and neural prostheses and include design and testing of electrodes and stimulation techniques, the electrical properties of tissues and cells, and computational neuroscience with applications in restoration of bladder function, treatment of movement disorders with deep brain stimulation, and treatment of chronic pain.
Awards, Honors, and Distinctions
- Capers & Marion McDonald Award for Excellence in Teaching and Research. Pratt School of Engineering. 2018
- Javits Neuroscience Investigator Award. NIH-NINDS . 2015
- Scholar / Teacher of the Year Award. Duke University. 2014
- Outstanding Postdoc Mentor. Duke University. 2013
- Fellow. Biomedical Engineering Society. 2011
- Fellow. American Institute for Medical and Biological Engineering. 2007
- BME 394: Projects in Biomedical Engineering (GE)
- BME 493: Projects in Biomedical Engineering (GE)
- BME 494: Projects in Biomedical Engineering (GE)
- BME 504: Fundamentals of Electrical Stimulation of the Nervous System (EL, GE)
- BME 515: Neural Prosthetic Systems (GE, EL, IM)
- BME 791: Graduate Independent Study
- BME 792: Continuation of Graduate Independent Study
- BME 804: Developments in Neural Engineering
- NEUROBIO 393: Research Independent Study
- NEUROBIO 793: Research in Neurobiology
- NEUROSCI 504: Fundamentals of Electrical Stimulation of the Nervous System (EL, GE)
- NEUROSCI 515: Neural Prosthetic Systems (GE, EL, IM)
In the News
- Light-Based Deep Brain Stimulation Relieves Symptoms of Parkinson’s Disease (Apr 28, 2020 | Pratt School of Engineering)
- Duke Awards Distinguished Professorships, Inducts New Bass Society Members (May 5, 2016)
- Deep Brain Stimulation as Treatment for Parkinson’s (Nov 10, 2015 | Duke Research Blog)
- Trying a New Pulse for Pain Relief (Nov 1, 2015)
- Biomedical Device students face engineering and business challenges while helping to fill clinical needs (Jul 8, 2015)
- Duke neuroscientist wins $4 million grant to study Parkinson's disease (Jun 26, 2015 | The News & Observer)
- Allen Song Named Interim Director of Brain Institute (Jun 26, 2015)
- Warren Grill on Using Deep Brain Stimulation to Treat Parkinson's (Jun 24, 2015)
- DIBS Director Takes New Role at Penn (Jun 16, 2015)
- Warren Grill comments: Brain implant trials raise ethical concerns (Jun 15, 2015 | Science Magazine)
- Nita Farahany Q-and-A: Neuroscience and the law (May 5, 2015 | Bio Edge)
- Peña, E; Pelot, NA; Grill, WM, Non-monotonic kilohertz frequency neural block thresholds arise from amplitude- and frequency-dependent charge imbalance., Scientific Reports, vol 11 no. 1 (2021) [10.1038/s41598-021-84503-3] [abs].
- Krauss, JK; Lipsman, N; Aziz, T; Boutet, A; Brown, P; Chang, JW; Davidson, B; Grill, WM; Hariz, MI; Horn, A; Schulder, M; Mammis, A; Tass, PA; Volkmann, J; Lozano, AM, Technology of deep brain stimulation: current status and future directions., Nature Reviews. Neurology, vol 17 no. 2 (2021), pp. 75-87 [10.1038/s41582-020-00426-z] [abs].
- Hokanson, JA; Langdale, CL; Milliken, PH; Sridhar, A; Grill, WM, Effects of intravesical prostaglandin E2 on bladder function are preserved in capsaicin-desensitized rats., American Journal of Physiology. Renal Physiology, vol 320 no. 2 (2021), pp. F212-F223 [10.1152/ajprenal.00302.2020] [abs].
- Hokanson, JA; Langdale, CL; Sridhar, A; Milliken, P; Grill, WM, State-dependent bioelectronic interface to control bladder function., Scientific Reports, vol 11 no. 1 (2021) [10.1038/s41598-020-79493-7] [abs].
- Pelot, NA; Catherall, DC; Thio, BJ; Titus, ND; Liang, ED; Henriquez, CS; Grill, WM, Excitation properties of computational models of unmyelinated peripheral axons., Journal of Neurophysiology, vol 125 no. 1 (2021), pp. 86-104 [10.1152/jn.00315.2020] [abs].