Sallie Robey Permar

Sallie Robey Permar

Wilburt C. Davison Distinguished Professor

Dr. Permar's work focuses on the development of vaccines to prevent vertical transmission of neonatal viral pathogens. She has utilized the nonhuman primate model of HIV/AIDS to characterize the virus-specific immune responses and virus evolution in breast milk and develop a maternal vaccine regimen for protection against breast milk transmission of HIV. In addition, Dr. Permar's lab has advanced the understanding of HIV-specific immune responses and virus evolution in vertically-transmitting and nontransmitting HIV-infected women, defining maternal immune responses that may protect against neonatal transmission of HIV. Importantly, Dr. Permar has established a nonhuman primate model of congenital CMV infection adn is using this model to establish the maternal immune responses that are necessary for protection against placental virus transmission. Finally, Dr. Permar is studying the impact and prevention of postnatal CMV transmission in preterm infants.

Appointments and Affiliations

  • Wilburt C. Davison Distinguished Professor
  • Professor of Pediatrics
  • Professor of Molecular Genetics and Microbiology
  • Professor in Immunology
  • Professor of Pathology
  • Affiliate, Duke Global Health Institute
  • Associate of the Duke Initiative for Science & Society
  • Core Faculty in Innovation & Entrepreneurship
  • Member of the Duke Human Vaccine Institute

Contact Information

Education

  • Children's Hospital Boston, 2009
  • Children's Hospital Boston, 2007
  • Ph.D. Johns Hopkins University, 2004
  • M.D. Harvard Medical School, 2004

Awards, Honors, and Distinctions

  • American Society of Clinical Investigation Inductee. ASCI. 2016
  • Young Investigator Award. Pediatric Infectious Diseases Society. 2015
  • Young Investigator Award. Society for Pediatric Research. 2014
  • Young Investigator Award. Society for Pediatrics Research. 2014
  • Presidential Early Career Awards for Scientists and Engineers. President of the United States of America. 2012

Courses Taught

  • IMMUNOL 493: Research Independent Study
  • IMMUNOL 494: Research Independent Study
  • PATHOL 793: Research Independent Study

In the News

Representative Publications

  • Weimer, KED; Kelly, MS; Permar, SR; Clark, RH; Greenberg, RG, Association of Adverse Hearing, Growth, and Discharge Age Outcomes With Postnatal Cytomegalovirus Infection in Infants With Very Low Birth Weight., Jama Pediatr, vol 174 no. 2 (2020), pp. 133-140 [10.1001/jamapediatrics.2019.4532] [abs].
  • Fouda, GG; De Paris, K; Levy, O; Marchant, A; Gray, G; Permar, S; Marovich, M; Singh, A, Immunological mechanisms of inducing HIV immunity in infants., Vaccine, vol 38 no. 3 (2020), pp. 411-415 [10.1016/j.vaccine.2019.11.011] [abs].
  • Van Rompay, KKA; Keesler, RI; Ardeshir, A; Watanabe, J; Usachenko, J; Singapuri, A; Cruzen, C; Bliss-Moreau, E; Murphy, AM; Yee, JL; Webster, H; Dennis, M; Singh, T; Heimsath, H; Lemos, D; Stuart, J; Morabito, KM; Foreman, BM; Burgomaster, KE; Noe, AT; Dowd, KA; Ball, E; Woolard, K; Presicce, P; Kallapur, SG; Permar, SR; Foulds, KE; Coffey, LL; Pierson, TC; Graham, BS, DNA vaccination before conception protects Zika virus-exposed pregnant macaques against prolonged viremia and improves fetal outcomes., Sci Transl Med, vol 11 no. 523 (2019) [10.1126/scitranslmed.aay2736] [abs].
  • Hompe, ED; Jacobson, DL; Eudailey, JA; Butler, K; Edwards, W; Pollara, J; Brummel, SS; Fouda, GG; Chinula, L; Kamanga, M; Kinikar, A; Moodley, D; Owor, M; Fowler, MG; Permar, SR, Maternal Humoral Immune Responses Do Not Predict Postnatal HIV-1 Transmission Risk in Antiretroviral-Treated Mothers from the IMPAACT PROMISE Study., Msphere, vol 4 no. 5 (2019) [10.1128/mSphere.00716-19] [abs].
  • Coppola, T; Mangold, JF; Cantrell, S; Permar, SR, Impact of Maternal Immunity on Congenital Cytomegalovirus Birth Prevalence and Infant Outcomes: A Systematic Review., Vaccines, vol 7 no. 4 (2019) [10.3390/vaccines7040129] [abs].
  • Goswami, R; Nelson, AN; Tu, JJ; Dennis, M; Feng, L; Kumar, A; Mangold, J; Mangan, RJ; Mattingly, C; Curtis, AD; Obregon-Perko, V; Mavigner, M; Pollara, J; Shaw, GM; Bar, KJ; Chahroudi, A; De Paris, K; Chan, C; Van Rompay, KKA; Permar, SR, Analytical Treatment Interruption after Short-Term Antiretroviral Therapy in a Postnatally Simian-Human Immunodeficiency Virus-Infected Infant Rhesus Macaque Model., Mbio, vol 10 no. 5 (2019) [10.1128/mBio.01971-19] [abs].
  • Maness, NJ; Schouest, B; Singapuri, A; Dennis, M; Gilbert, MH; Bohm, RP; Schiro, F; Aye, PP; Baker, K; Van Rompay, KKA; Lackner, AA; Bonaldo, MC; Blair, RV; Permar, SR; Coffey, LL; Panganiban, AT; Magnani, D, Postnatal Zika virus infection of nonhuman primate infants born to mothers infected with homologous Brazilian Zika virus., Scientific Reports, vol 9 no. 1 (2019) [10.1038/s41598-019-49209-7] [abs].
  • Nelson, AN; Goswami, R; Dennis, M; Tu, J; Mangan, RJ; Saha, PT; Cain, DW; Curtis, AD; Shen, X; Shaw, GM; Bar, K; Hudgens, M; Pollara, J; De Paris, K; Van Rompay, KKA; Permar, SR, Simian-Human Immunodeficiency Virus SHIV.CH505-Infected Infant and Adult Rhesus Macaques Exhibit Similar Env-Specific Antibody Kinetics, despite Distinct T-Follicular Helper and Germinal Center B Cell Landscapes., J Virol, vol 93 no. 15 (2019) [10.1128/JVI.00168-19] [abs].
  • Breitbach, ME; Newman, CM; Dudley, DM; Stewart, LM; Aliota, MT; Koenig, MR; Shepherd, PM; Yamamoto, K; Crooks, CM; Young, G; Semler, MR; Weiler, AM; Barry, GL; Heimsath, H; Mohr, EL; Eichkoff, J; Newton, W; Peterson, E; Schultz-Darken, N; Permar, SR; Dean, H; Capuano, S; Osorio, JE; Friedrich, TC; O'Connor, DH, Primary infection with dengue or Zika virus does not affect the severity of heterologous secondary infection in macaques., Plos Pathog, vol 15 no. 8 (2019) [10.1371/journal.ppat.1007766] [abs].
  • Singh, T; Lopez, CA; Giuberti, C; Dennis, ML; Itell, HL; Heimsath, HJ; Webster, HS; Roark, HK; Merçon de Vargas, PR; Hall, A; Corey, RG; Swamy, GK; Dietze, R; Lazear, HM; Permar, SR, Efficient transplacental IgG transfer in women infected with Zika virus during pregnancy., Plos Neglected Tropical Diseases, vol 13 no. 8 (2019) [10.1371/journal.pntd.0007648] [abs].
  • Saccoccio, FM; Jenks, JA; Itell, HL; Li, SH; Berry, M; Pollara, J; Casper, C; Gantt, S; Permar, SR, Humoral Immune Correlates for Prevention of Postnatal Cytomegalovirus Acquisition., J Infect Dis, vol 220 no. 5 (2019), pp. 772-780 [10.1093/infdis/jiz192] [abs].
  • Singh, A; Permar, S; Kollmann, TR; Levy, O; Marovich, M; De Paris, K, AIDS Vaccine Research Subcommittee (AVRS) Consultation: Early-Life Immunization Strategies against HIV Acquisition., Msphere, vol 4 no. 4 (2019) [10.1128/mSphere.00320-19] [abs].
  • Mangan, RJ; Stamper, L; Ohashi, T; Eudailey, JA; Go, EP; Jaeger, FH; Itell, HL; Watts, BE; Fouda, GG; Erickson, HP; Alam, SM; Desaire, H; Permar, SR, Determinants of Tenascin-C and HIV-1 envelope binding and neutralization., Mucosal Immunol, vol 12 no. 4 (2019), pp. 1004-1012 [10.1038/s41385-019-0164-2] [abs].
  • Martinez, DR; Fong, Y; Li, SH; Yang, F; Jennewein, MF; Weiner, JA; Harrell, EA; Mangold, JF; Goswami, R; Seage, GR; Alter, G; Ackerman, ME; Peng, X; Fouda, GG; Permar, SR, Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women., Cell, vol 178 no. 1 (2019), pp. 190-201.e11 [10.1016/j.cell.2019.05.046] [abs].
  • Pollara, J; Jones, DI; Huffman, T; Edwards, RW; Dennis, M; Li, SH; Jha, S; Goodman, D; Kumar, A; LaBranche, CC; Montefiori, DC; Fouda, GG; Hope, TJ; Tomaras, GD; Staats, HF; Ferrari, G; Permar, SR, Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models., J Virol, vol 93 no. 10 (2019) [10.1128/JVI.02119-18] [abs].
  • Tay, MZ; Kunz, EL; Deal, A; Zhang, L; Seaton, KE; Rountree, W; Eudailey, JA; Heptinstall, J; McRaven, MD; Matias, E; McGuire, E; Yates, NL; Perez, LG; Montefiori, DC; Overman, RG; Hope, TJ; Shen, X; Kalilani, L; Fouda, GG; Tomaras, GD; Permar, SR, Rare Detection of Antiviral Functions of Polyclonal IgA Isolated from Plasma and Breast Milk Compartments in Women Chronically Infected with HIV-1., J Virol, vol 93 no. 7 (2019) [10.1128/JVI.02084-18] [abs].
  • Dennis, M; Eudailey, J; Pollara, J; McMillan, AS; Cronin, KD; Saha, PT; Curtis, AD; Hudgens, MG; Fouda, GG; Ferrari, G; Alam, M; Van Rompay, KKA; De Paris, K; Permar, S; Shen, X, Coadministration of CH31 Broadly Neutralizing Antibody Does Not Affect Development of Vaccine-Induced Anti-HIV-1 Envelope Antibody Responses in Infant Rhesus Macaques., J Virol, vol 93 no. 5 (2019) [10.1128/JVI.01783-18] [abs].
  • Nelson, CS; Vera Cruz, D; Su, M; Xie, G; Vandergrift, N; Pass, RF; Forman, M; Diener-West, M; Koelle, K; Arav-Boger, R; Permar, SR, Intrahost Dynamics of Human Cytomegalovirus Variants Acquired by Seronegative Glycoprotein B Vaccinees., J Virol, vol 93 no. 5 (2019) [10.1128/JVI.01695-18] [abs].
  • Jenks, JA; Goodwin, ML; Permar, SR, The Roles of Host and Viral Antibody Fc Receptors in Herpes Simplex Virus (HSV) and Human Cytomegalovirus (HCMV) Infections and Immunity., Frontiers in Immunology, vol 10 (2019) [10.3389/fimmu.2019.02110] [abs].
  • Shah, SV; Manickam, C; Ram, DR; Kroll, K; Itell, H; Permar, SR; Barouch, DH; Klatt, NR; Reeves, RK, CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques., Cell Reports, vol 25 no. 10 (2018), pp. 2766-2774.e3 [10.1016/j.celrep.2018.11.020] [abs].
  • Himes, JE; Goswami, R; Mangan, RJ; Kumar, A; Jeffries, TL; Eudailey, JA; Heimsath, H; Nguyen, QN; Pollara, J; LaBranche, C; Chen, M; Vandergrift, NA; Peacock, JW; Schiro, F; Midkiff, C; Ferrari, G; Montefiori, DC; Hernandez, XA; Aye, PP; Permar, SR, Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys., Mucosal Immunol, vol 11 no. 6 (2018), pp. 1716-1726 [10.1038/s41385-018-0067-7] [abs].
  • Phillips, B; Van Rompay, KKA; Rodriguez-Nieves, J; Lorin, C; Koutsoukos, M; Tomai, M; Fox, CB; Eudailey, J; Dennis, M; Alam, SM; Hudgens, M; Fouda, G; Pollara, J; Moody, A; Shen, X; Ferrari, G; Permar, S; De Paris, K, Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques., J Virol, vol 92 no. 20 (2018) [10.1128/JVI.01051-18] [abs].
  • Permar, S; Levy, O; Kollman, TR; Singh, A; De Paris, K, Early Life HIV-1 Immunization: Providing a Window for Protection Before Sexual Debut., Aids Res Hum Retroviruses, vol 34 no. 10 (2018), pp. 823-827 [10.1089/AID.2018.0018] [abs].
  • Martinez, DR; Fouda, GG; Peng, X; Ackerman, ME; Permar, SR, Noncanonical placental Fc receptors: What is their role in modulating transplacental transfer of maternal IgG?, Plos Pathog, vol 14 no. 8 (2018) [10.1371/journal.ppat.1007161] [abs].
  • Coffey, LL; Keesler, RI; Pesavento, PA; Woolard, K; Singapuri, A; Watanabe, J; Cruzen, C; Christe, KL; Usachenko, J; Yee, J; Heng, VA; Bliss-Moreau, E; Reader, JR; von Morgenland, W; Gibbons, AM; Jackson, K; Ardeshir, A; Heimsath, H; Permar, S; Senthamaraikannan, P; Presicce, P; Kallapur, SG; Linnen, JM; Gao, K; Orr, R; MacGill, T; McClure, M; McFarland, R; Morrison, JH; Van Rompay, KKA, Intraamniotic Zika virus inoculation of pregnant rhesus macaques produces fetal neurologic disease., Nature Communications, vol 9 no. 1 (2018) [10.1038/s41467-018-04777-6] [abs].
  • Nelson, CS; Huffman, T; Jenks, JA; Cisneros de la Rosa, E; Xie, G; Vandergrift, N; Pass, RF; Pollara, J; Permar, SR, HCMV glycoprotein B subunit vaccine efficacy mediated by nonneutralizing antibody effector functions., Proc Natl Acad Sci U S A, vol 115 no. 24 (2018), pp. 6267-6272 [10.1073/pnas.1800177115] [abs].
  • Ram, DR; Manickam, C; Hueber, B; Itell, HL; Permar, SR; Varner, V; Reeves, RK, Tracking KLRC2 (NKG2C)+ memory-like NK cells in SIV+ and rhCMV+ rhesus macaques., Plos Pathog, vol 14 no. 5 (2018) [10.1371/journal.ppat.1007104] [abs].
  • Permar, SR; Schleiss, MR; Plotkin, SA, Advancing Our Understanding of Protective Maternal Immunity as a Guide for Development of Vaccines To Reduce Congenital Cytomegalovirus Infections., J Virol, vol 92 no. 7 (2018) [10.1128/JVI.00030-18] [abs].
  • Kumar, A; Smith, CEP; Giorgi, EE; Eudailey, J; Martinez, DR; Yusim, K; Douglas, AO; Stamper, L; McGuire, E; LaBranche, CC; Montefiori, DC; Fouda, GG; Gao, F; Permar, SR, Infant transmitted/founder HIV-1 viruses from peripartum transmission are neutralization resistant to paired maternal plasma., Plos Pathog, vol 14 no. 4 (2018) [10.1371/journal.ppat.1006944] [abs].
  • Nguyen, QN; Martinez, DR; Himes, JE; Whitney Edwards, R; Han, Q; Kumar, A; Mangan, R; Nicely, NI; Xie, G; Vandergrift, N; Shen, X; Pollara, J; Permar, SR, Predominant envelope variable loop 2-specific and gp120-specific antibody-dependent cellular cytotoxicity antibody responses in acutely SIV-infected African green monkeys., Retrovirology, vol 15 no. 1 (2018) [10.1186/s12977-018-0406-5] [abs].
  • McGuire, EP; Fong, Y; Toote, C; Cunningham, CK; McFarland, EJ; Borkowsky, W; Barnett, S; Itell, HL; Kumar, A; Gray, G; McElrath, MJ; Tomaras, GD; Permar, SR; Fouda, GG, HIV-Exposed Infants Vaccinated with an MF59/Recombinant gp120 Vaccine Have Higher-Magnitude Anti-V1V2 IgG Responses than Adults Immunized with the Same Vaccine., J Virol, vol 92 no. 1 (2018) [10.1128/JVI.01070-17] [abs].
  • Fouda, GG; Martinez, DR; Swamy, GK; Permar, SR, The Impact of IgG transplacental transfer on early life immunity., Immunohorizons, vol 2 no. 1 (2018), pp. 14-25 [10.4049/immunohorizons.1700057] [abs].
  • Nelson, CS; Herold, BC; Permar, SR, A new era in cytomegalovirus vaccinology: considerations for rational design of next-generation vaccines to prevent congenital cytomegalovirus infection., Npj Vaccines, vol 3 (2018) [10.1038/s41541-018-0074-4] [abs].
  • Kaur, A; Itell, HL; Ehlinger, EP; Varner, V; Gantt, S; Permar, SR, Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys., Plos One, vol 13 no. 10 (2018) [10.1371/journal.pone.0206330] [abs].
  • Itell, HL; Nelson, CS; Martinez, DR; Permar, SR, Maternal immune correlates of protection against placental transmission of cytomegalovirus., Placenta, vol 60 Suppl 1 (2017), pp. S73-S79 [10.1016/j.placenta.2017.04.011] [abs].
  • Schleiss, MR; Permar, SR; Plotkin, SA, Progress toward Development of a Vaccine against Congenital Cytomegalovirus Infection., Clin Vaccine Immunol, vol 24 no. 12 (2017) [10.1128/CVI.00268-17] [abs].
  • Voronin, Y; Jani, I; Graham, BS; Cunningham, CK; Mofenson, LM; Musoke, PM; Permar, SR; Scarlatti, G, Recent progress in immune-based interventions to prevent HIV-1 transmission to children., Journal of the International Aids Society, vol 20 no. 4 (2017) [10.1002/jia2.25038] [abs].
  • Lantos, PM; Hoffman, K; Permar, SR; Jackson, P; Hughes, BL; Swamy, GK, Geographic Disparities in Cytomegalovirus Infection During Pregnancy., J Pediatric Infect Dis Soc, vol 6 no. 3 (2017), pp. e55-e61 [10.1093/jpids/piw088] [abs].
  • Mutucumarana, CP; Eudailey, J; McGuire, EP; Vandergrift, N; Tegha, G; Chasela, C; Ellington, S; van der Horst, C; Kourtis, AP; Permar, SR; Fouda, GG, Maternal Humoral Immune Correlates of Peripartum Transmission of Clade C HIV-1 in the Setting of Peripartum Antiretrovirals., Clin Vaccine Immunol, vol 24 no. 8 (2017) [10.1128/CVI.00062-17] [abs].
  • Itell, HL; Kaur, A; Deere, JD; Barry, PA; Permar, SR, Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections., Current Opinion in Virology, vol 25 (2017), pp. 126-133 [10.1016/j.coviro.2017.08.005] [abs].
  • Nelson, CS; Cruz, DV; Tran, D; Bialas, KM; Stamper, L; Wu, H; Gilbert, M; Blair, R; Alvarez, X; Itell, H; Chen, M; Deshpande, A; Chiuppesi, F; Wussow, F; Diamond, DJ; Vandergrift, N; Walter, MR; Barry, PA; Cohen-Wolkowiez, M; Koelle, K; Kaur, A; Permar, SR, Preexisting antibodies can protect against congenital cytomegalovirus infection in monkeys., Jci Insight, vol 2 no. 13 (2017) [10.1172/jci.insight.94002] [abs].
  • Martinez, DR; Vandergrift, N; Douglas, AO; McGuire, E; Bainbridge, J; Nicely, NI; Montefiori, DC; Tomaras, GD; Fouda, GG; Permar, SR, Maternal Binding and Neutralizing IgG Responses Targeting the C-Terminal Region of the V3 Loop Are Predictive of Reduced Peripartum HIV-1 Transmission Risk., J Virol, vol 91 no. 9 (2017) [10.1128/JVI.02422-16] [abs].
  • Fan, Q; Nelson, CS; Bialas, KM; Chiuppesi, F; Amos, J; Gurley, TC; Marshall, DJ; Eudailey, J; Heimsath, H; Himes, J; Deshpande, A; Walter, MR; Wussow, F; Diamond, DJ; Barry, PA; Moody, MA; Kaur, A; Permar, SR, Plasmablast Response to Primary Rhesus Cytomegalovirus (CMV) Infection in a Monkey Model of Congenital CMV Transmission., Clin Vaccine Immunol, vol 24 no. 5 (2017) [10.1128/CVI.00510-16] [abs].
  • Nguyen, SM; Antony, KM; Dudley, DM; Kohn, S; Simmons, HA; Wolfe, B; Salamat, MS; Teixeira, LBC; Wiepz, GJ; Thoong, TH; Aliota, MT; Weiler, AM; Barry, GL; Weisgrau, KL; Vosler, LJ; Mohns, MS; Breitbach, ME; Stewart, LM; Rasheed, MN; Newman, CM; Graham, ME; Wieben, OE; Turski, PA; Johnson, KM; Post, J; Hayes, JM; Schultz-Darken, N; Schotzko, ML; Eudailey, JA; Permar, SR; Rakasz, EG; Mohr, EL; Capuano, S; Tarantal, AF; Osorio, JE; O'Connor, SL; Friedrich, TC; O'Connor, DH; Golos, TG, Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques., Plos Pathog, vol 13 no. 5 (2017) [10.1371/journal.ppat.1006378] [abs].
  • Becker-Dreps, S; Choi, WS; Stamper, L; Vilchez, S; Velasquez, DE; Moon, S-S; Hudgens, MG; Jiang, B; Permar, SR, Innate Immune Factors in Mothers' Breast Milk and Their Lack of Association With Rotavirus Vaccine Immunogenicity in Nicaraguan Infants., J Pediatric Infect Dis Soc, vol 6 no. 1 (2017), pp. 87-90 [10.1093/jpids/piv076] [abs].
  • Fouda, GG; Eudailey, J; Kunz, EL; Amos, JD; Liebl, BE; Himes, J; Boakye-Agyeman, F; Beck, K; Michaels, AJ; Cohen-Wolkowiez, M; Haynes, BF; Reimann, KA; Permar, SR, Systemic administration of an HIV-1 broadly neutralizing dimeric IgA yields mucosal secretory IgA and virus neutralization., Mucosal Immunol, vol 10 no. 1 (2017), pp. 228-237 [10.1038/mi.2016.32] [abs].
  • Mwila, K; Chilengi, R; Simuyandi, M; Permar, SR; Becker-Dreps, S, Contribution of Maternal Immunity to Decreased Rotavirus Vaccine Performance in Low- and Middle-Income Countries., Clin Vaccine Immunol, vol 24 no. 1 (2017) [10.1128/CVI.00405-16] [abs].
  • Douglas, AO; Martinez, DR; Permar, SR, The Role of Maternal HIV Envelope-Specific Antibodies and Mother-to-Child Transmission Risk., Frontiers in Immunology, vol 8 (2017) [10.3389/fimmu.2017.01091] [abs].
  • Mwila-Kazimbaya, K; Garcia, MP; Bosomprah, S; Laban, NM; Chisenga, CC; Permar, SR; Simuyandi, M; Munsaka, S; Chilengi, R, Effect of innate antiviral glycoproteins in breast milk on seroconversion to rotavirus vaccine (Rotarix) in children in Lusaka, Zambia., Plos One, vol 12 no. 12 (2017) [10.1371/journal.pone.0189351] [abs].
  • Bialas, KM; Westreich, D; Cisneros de la Rosa, E; Nelson, CS; Kauvar, LM; Fu, T-M; Permar, SR, Maternal Antibody Responses and Nonprimary Congenital Cytomegalovirus Infection of HIV-1-Exposed Infants., J Infect Dis, vol 214 no. 12 (2016), pp. 1916-1923 [10.1093/infdis/jiw487] [abs].
  • Aliota, MT; Dudley, DM; Newman, CM; Mohr, EL; Gellerup, DD; Breitbach, ME; Buechler, CR; Rasheed, MN; Mohns, MS; Weiler, AM; Barry, GL; Weisgrau, KL; Eudailey, JA; Rakasz, EG; Vosler, LJ; Post, J; Capuano, S; Golos, TG; Permar, SR; Osorio, JE; Friedrich, TC; O'Connor, SL; O'Connor, DH, Heterologous Protection against Asian Zika Virus Challenge in Rhesus Macaques., Plos Neglected Tropical Diseases, vol 10 no. 12 (2016) [10.1371/journal.pntd.0005168] [abs].
  • Nguyen, QN; Himes, JE; Martinez, DR; Permar, SR, The Impact of the Gut Microbiota on Humoral Immunity to Pathogens and Vaccination in Early Infancy., Plos Pathog, vol 12 no. 12 (2016) [10.1371/journal.ppat.1005997] [abs].
  • Himes, JE; Ho, C; Nguyen, QN; Amos, JD; Xu, H; Chan, C; Chow, S-C; Ochsenbauer, C; Kaidarova, Z; Keating, SM; Fouda, GG; Permar, SR, Characterization of Simian Immunodeficiency Virus Variants Anatomically Compartmentalized in Plasma and Milk in Chronically Infected African Green Monkeys., J Virol, vol 90 no. 19 (2016), pp. 8795-8808 [10.1128/JVI.00701-16] [abs].
  • Zhang, R; Alam, SM; Yu, J-S; Scearce, R; Lockwood, B; Hwang, K-K; Parks, R; Permar, S; Brandtzaeg, P; Haynes, BF; Liao, H-X, Novel Monoclonal Antibodies for Studies of Human and Rhesus Macaque Secretory Component and Human J-Chain., Monoclonal Antibodies in Immunodiagnosis and Immunotherapy, vol 35 no. 4 (2016), pp. 217-226 [10.1089/mab.2016.0014] [abs].
  • Zhang, R; Martinez, DR; Nguyen, QN; Pollara, J; Arifin, T; Stolarchuk, C; Foulger, A; Amos, JD; Parks, R; Himes, JE; Wang, M; Edwards, RW; Trama, AM; Vandergrift, N; Colvin, L; Dewar, K; Juretic, N; Wasserscheid, J; Ferrari, G; Liao, H-X; Permar, SR, Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus., Nature Communications, vol 7 (2016) [10.1038/ncomms12131] [abs].
  • Mukhopadhyay, S; Meyer, SA; Permar, SR; Puopolo, KM, Symptomatic Postnatal Cytomegalovirus Testing among Very Low-Birth-Weight Infants: Indications and Outcomes., Am J Perinatol, vol 33 no. 9 (2016), pp. 894-902 [10.1055/s-0036-1581080] [abs].
  • Dudley, DM; Aliota, MT; Mohr, EL; Weiler, AM; Lehrer-Brey, G; Weisgrau, KL; Mohns, MS; Breitbach, ME; Rasheed, MN; Newman, CM; Gellerup, DD; Moncla, LH; Post, J; Schultz-Darken, N; Schotzko, ML; Hayes, JM; Eudailey, JA; Moody, MA; Permar, SR; O'Connor, SL; Rakasz, EG; Simmons, HA; Capuano, S; Golos, TG; Osorio, JE; Friedrich, TC; O'Connor, DH, A rhesus macaque model of Asian-lineage Zika virus infection., Nature Communications, vol 7 (2016) [10.1038/ncomms12204] [abs].
  • Nelson, CS; Pollara, J; Kunz, EL; Jeffries, TL; Duffy, R; Beck, C; Stamper, L; Wang, M; Shen, X; Pickup, DJ; Staats, HF; Hudgens, MG; Kepler, TB; Montefiori, DC; Moody, MA; Tomaras, GD; Liao, H-X; Haynes, BF; Ferrari, G; Fouda, GGA; Permar, SR, Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk., J Virol, vol 90 no. 10 (2016), pp. 4951-4965 [10.1128/JVI.00335-16] [abs].
  • Jeffries, TL; Sacha, CR; Pollara, J; Himes, J; Jaeger, FH; Dennison, SM; McGuire, E; Kunz, E; Eudailey, JA; Trama, AM; LaBranche, C; Fouda, GG; Wiehe, K; Montefiori, DC; Haynes, BF; Liao, H-X; Ferrari, G; Alam, SM; Moody, MA; Permar, SR, The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells., Mucosal Immunol, vol 9 no. 2 (2016), pp. 414-427 [10.1038/mi.2015.70] [abs].
  • Martinez, DR; Permar, SR; Fouda, GG, Contrasting Adult and Infant Immune Responses to HIV Infection and Vaccination., Clin Vaccine Immunol, vol 23 no. 2 (2016), pp. 84-94 [10.1128/CVI.00565-15] [abs].
  • Bialas, KM; Permar, SR, The March towards a Vaccine for Congenital CMV: Rationale and Models., Plos Pathog, vol 12 no. 2 (2016) [10.1371/journal.ppat.1005355] [abs].
  • Mansour, RG; Stamper, L; Jaeger, F; McGuire, E; Fouda, G; Amos, J; Barbas, K; Ohashi, T; Alam, SM; Erickson, H; Permar, SR, The Presence and Anti-HIV-1 Function of Tenascin C in Breast Milk and Genital Fluids., Plos One, vol 11 no. 5 (2016) [10.1371/journal.pone.0155261] [abs].
  • Kelly, MS; Benjamin, DK; Puopolo, KM; Laughon, MM; Clark, RH; Mukhopadhyay, S; Smith, PB; Permar, SR, Postnatal Cytomegalovirus Infection and the Risk for Bronchopulmonary Dysplasia., Jama Pediatr, vol 169 no. 12 (2015) [10.1001/jamapediatrics.2015.3785] [abs].
  • Bialas, KM; Tanaka, T; Tran, D; Varner, V; Cisneros De La Rosa, E; Chiuppesi, F; Wussow, F; Kattenhorn, L; Macri, S; Kunz, EL; Estroff, JA; Kirchherr, J; Yue, Y; Fan, Q; Lauck, M; O'Connor, DH; Hall, AHS; Xavier, A; Diamond, DJ; Barry, PA; Kaur, A; Permar, SR, Maternal CD4+ T cells protect against severe congenital cytomegalovirus disease in a novel nonhuman primate model of placental cytomegalovirus transmission., Proc Natl Acad Sci U S A, vol 112 no. 44 (2015), pp. 13645-13650 [10.1073/pnas.1511526112] [abs].
  • Wahl, A; Baker, C; Spagnuolo, RA; Stamper, LW; Fouda, GG; Permar, SR; Hinde, K; Kuhn, L; Bode, L; Aldrovandi, GM; Garcia, JV, Breast Milk of HIV-Positive Mothers Has Potent and Species-Specific In Vivo HIV-Inhibitory Activity., J Virol, vol 89 no. 21 (2015), pp. 10868-10878 [10.1128/JVI.01702-15] [abs].
  • Amos, JD; Himes, JE; Armand, L; Gurley, TC; Martinez, DR; Colvin, L; Beck, K; Overman, RG; Liao, H-X; Moody, MA; Permar, SR, Rapid Development of gp120-Focused Neutralizing B Cell Responses during Acute Simian Immunodeficiency Virus Infection of African Green Monkeys., J Virol, vol 89 no. 18 (2015), pp. 9485-9498 [10.1128/JVI.01564-15] [abs].
  • Shen, X; Duffy, R; Howington, R; Cope, A; Sadagopal, S; Park, H; Pal, R; Kwa, S; Ding, S; Yang, OO; Fouda, GG; Le Grand, R; Bolton, D; Esteban, M; Phogat, S; Roederer, M; Amara, RR; Picker, LJ; Seder, RA; McElrath, MJ; Barnett, S; Permar, SR; Shattock, R; DeVico, AL; Felber, BK; Pavlakis, GN; Pantaleo, G; Korber, BT; Montefiori, DC; Tomaras, GD, Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates., J Virol, vol 89 no. 16 (2015), pp. 8643-8650 [10.1128/JVI.03635-14] [abs].
  • Richard, J; Veillette, M; Brassard, N; Iyer, SS; Roger, M; Martin, L; Pazgier, M; Schön, A; Freire, E; Routy, J-P; Smith, AB; Park, J; Jones, DM; Courter, JR; Melillo, BN; Kaufmann, DE; Hahn, BH; Permar, SR; Haynes, BF; Madani, N; Sodroski, JG; Finzi, A, CD4 mimetics sensitize HIV-1-infected cells to ADCC., Proc Natl Acad Sci U S A, vol 112 no. 20 (2015), pp. E2687-E2694 [10.1073/pnas.1506755112] [abs].
  • Fouda, GG; Moody, MA; Permar, SR, Antibodies for prevention of mother-to-child transmission of HIV-1., Curr Opin Hiv Aids, vol 10 no. 3 (2015), pp. 177-182 [10.1097/COH.0000000000000150] [abs].
  • Fong, Y; Di, C; Permar, S, Change point testing in logistic regression models with interaction term., Stat Med, vol 34 no. 9 (2015), pp. 1483-1494 [10.1002/sim.6419] [abs].
  • Fouda, GG; Cunningham, CK; Permar, SR, Infant HIV-1 vaccines: supplementing strategies to reduce maternal-child transmission., Jama, vol 313 no. 15 (2015), pp. 1513-1514 [10.1001/jama.2015.1382] [abs].
  • Sacha, CR; Vandergrift, N; Jeffries, TL; McGuire, E; Fouda, GG; Liebl, B; Marshall, DJ; Gurley, TC; Stiegel, L; Whitesides, JF; Friedman, J; Badiabo, A; Foulger, A; Yates, NL; Tomaras, GD; Kepler, TB; Liao, HX; Haynes, BF; Moody, MA; Permar, SR, Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women., Mucosal Immunol, vol 8 no. 2 (2015), pp. 316-326 [10.1038/mi.2014.69] [abs].
  • Bialas, KM; Swamy, GK; Permar, SR, Perinatal cytomegalovirus and varicella zoster virus infections: epidemiology, prevention, and treatment., Clin Perinatol, vol 42 no. 1 (2015), pp. 61-viii [10.1016/j.clp.2014.10.006] [abs].
  • Fouda, GG; Cunningham, CK; McFarland, EJ; Borkowsky, W; Muresan, P; Pollara, J; Song, LY; Liebl, BE; Whitaker, K; Shen, X; Vandergrift, NA; Overman, RG; Yates, NL; Moody, MA; Fry, C; Kim, JH; Michael, NL; Robb, M; Pitisuttithum, P; Kaewkungwal, J; Nitayaphan, S; Rerks-Ngarm, S; Liao, H-X; Haynes, BF; Montefiori, DC; Ferrari, G; Tomaras, GD; Permar, SR, Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses., J Infect Dis, vol 211 no. 4 (2015), pp. 508-517 [10.1093/infdis/jiu444] [abs].
  • Bialas, KM; Swamy, GK; Permar, SR, Perinatal cytomegalovirus infections: Epidemiology, prevention, and treatment, Neoreviews, vol 16 no. 4 (2015), pp. e231-e235 [10.1542/neo.16-4-e231] [abs].
  • Smith, SD; Amos, JD; Beck, KN; Colvin, LM; Franke, KS; Liebl, BE; Permar, SR, Refinement of a protocol for the induction of lactation in nonpregnant nonhuman primates by using exogenous hormone treatment., Journal of the American Association for Laboratory Animal Science : Jaalas, vol 53 no. 6 (2014), pp. 700-707 [abs].
  • Chahroudi, A; Cartwright, E; Carnathan, DG; Lee, ST; Lawson, B; Carnathan, PM; Hashempoor, T; Murphy, MK; Meeker, T; Ehnert, S; Souder, C; Else, JG; Cohen, J; Vanderford, TH; Permar, SR; Derdeyn, CA; Villinger, F; Silvestri, G, TARGET CELL AVAILABILITY, RATHER THAN BREAST MILK SPECIFIC FACTORS, DICTATES MOTHER-TO-INFANT TRANSMISSION OF SIV, Journal of Medical Primatology, vol 43 no. 5 (2014), pp. 385-385 [abs].
  • Kaur, A; Barry, P; Bialas, K; Tran, D; Varner, V; Kunz, E; Amos, J; Kirchherr, J; Kattenhorn, L; Wachtman, L; Tanaka, T; Permar, SR, SUCCESSFUL DEVELOPMENT OF A NONHUMAN PRIMATE MODEL OF CONGENITAL CYTOMEGALOVIRUS TRANSMISSION, Journal of Medical Primatology, vol 43 no. 5 (2014), pp. 426-426 [abs].
  • Fouda, GG; Permar, SR, Immune-based interventions to prevent postnatal HIV-1 transmission., Trends Microbiol, vol 22 no. 8 (2014), pp. 425-427 [10.1016/j.tim.2014.04.009] [abs].
  • Madani, N; Princiotto, AM; Schön, A; LaLonde, J; Feng, Y; Freire, E; Park, J; Courter, JR; Jones, DM; Robinson, J; Liao, H-X; Moody, MA; Permar, S; Haynes, B; Smith, AB; Wyatt, R; Sodroski, J, CD4-mimetic small molecules sensitize human immunodeficiency virus to vaccine-elicited antibodies., J Virol, vol 88 no. 12 (2014), pp. 6542-6555 [10.1128/JVI.00540-14] [abs].
  • Permar, SR; Staats, HF, Which comes first: the antigen or the adjuvant?, J Clin Invest, vol 124 no. 6 (2014), pp. 2364-2365 [10.1172/JCI76263] [abs].
  • Chahroudi, A; Cartwright, E; Lee, ST; Mavigner, M; Carnathan, DG; Lawson, B; Carnathan, PM; Hashempoor, T; Murphy, MK; Meeker, T; Ehnert, S; Souder, C; Else, JG; Cohen, J; Collman, RG; Vanderford, TH; Permar, SR; Derdeyn, CA; Villinger, F; Silvestri, G, Target cell availability, rather than breast milk factors, dictates mother-to-infant transmission of SIV in sooty mangabeys and rhesus macaques., Plos Pathog, vol 10 no. 3 (2014) [10.1371/journal.ppat.1003958] [abs].
  • Meyer, SA; Westreich, DJ; Patel, E; Ehlinger, EP; Kalilani, L; Lovingood, RV; Denny, TN; Swamy, GK; Permar, SR, Postnatal cytomegalovirus exposure in infants of antiretroviral-treated and untreated HIV-infected mothers., Infect Dis Obstet Gynecol, vol 2014 (2014) [10.1155/2014/989721] [abs].
  • Fouda, GG; Jaeger, FH; Amos, JD; Ho, C; Kunz, EL; Anasti, K; Stamper, LW; Liebl, BE; Barbas, KH; Ohashi, T; Moseley, MA; Liao, H-X; Erickson, HP; Alam, SM; Permar, SR, Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk., Proc Natl Acad Sci U S A, vol 110 no. 45 (2013), pp. 18220-18225 [10.1073/pnas.1307336110] [abs].
  • Fouda, GG; Cunningham, CK; McFarland, EJ; Borkowsky, W; Muresan, P; Liebl, BE; Liao, H; Haynes, BF; Overman, R; Yates, NL; Tomaras, GD; Permar, SR, HIV-1 gp120 Vaccination Elicits a Robust and Durable Anti-V1/V2 IgG Response and Yet No HIV-1 Env-Specific IgA Response in HIV-Exposed Infants, Aids Research and Human Retroviruses, vol 29 no. 11 (2013), pp. A13-A14 [abs].
  • Kunz, E; Fouda, G; Ho, C; Amos, J; Colvin, L; Montefiori, D; Martelli, A; Allen, A; Aramand, L; Marshall, DJ; Letvin, NL; Staats, H; Pickup, D; Barnett, SC; Moody, MA; Haynes, BF; Liao, H; Permar, SR, Combined Mucosal and Systemic C.1086 Envelope Immunization of Lactating Monkeys Induces Potent IgA and Functional IgG Antibody Responses in Milk, Aids Research and Human Retroviruses, vol 29 no. 11 (2013), pp. A180-A180 [abs].
  • Sacha, CR; Vandergrift, N; Marshall, DJ; Gurley, TC; Stiegel, L; Whitesides, JF; Friedman, J; Fouda, GG; Liebl, B; McGuire, E; Foulger, A; Kepler, TB; Liao, H; Haynes, BF; Moody, MA; Permar, SR, Distinct VH Gene Usage and HIV Envelope Specificity of Colostrum and Peripheral B Cell Monoclonal Antibodies of HIV-Infected, Lactating African Women, Aids Research and Human Retroviruses, vol 29 no. 11 (2013), pp. A169-A170 [abs].
  • Amos, JD; Wilks, AB; Fouda, GG; Smith, SD; Colvin, L; Mahlokozera, T; Ho, C; Beck, K; Overman, RG; DeMarco, CT; Hodge, TL; LaBranche, CC; Montefiori, DC; Denny, TN; Liao, H-X; Tomaras, GD; Moody, MA; Permar, SR, Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys., J Virol, vol 87 no. 20 (2013), pp. 11121-11134 [10.1128/JVI.01887-13] [abs].
  • Ho, C; Wu, S; Amos, JD; Colvin, L; Smith, SD; Wilks, AB; Demarco, CT; Brinkley, C; Denny, TN; Schmitz, JE; Rodrigo, AG; Permar, SR, Transient compartmentalization of simian immunodeficiency virus variants in the breast milk of african green monkeys., J Virol, vol 87 no. 20 (2013), pp. 11292-11299 [10.1128/JVI.01643-13] [abs].
  • Permar, SR; Salazar, MG; Gao, F; Cai, F; Learn, GH; Kalilani, L; Hahn, BH; Shaw, GM; Salazar-Gonzalez, JF, Clonal amplification and maternal-infant transmission of nevirapine-resistant HIV-1 variants in breast milk following single-dose nevirapine prophylaxis., Retrovirology, vol 10 (2013) [10.1186/1742-4690-10-88] [abs].
  • Fouda, GGA; Amos, JD; Wilks, AB; Pollara, J; Ray, CA; Chand, A; Kunz, EL; Liebl, BE; Whitaker, K; Carville, A; Smith, S; Colvin, L; Pickup, DJ; Staats, HF; Overman, G; Eutsey-Lloyd, K; Parks, R; Chen, H; Labranche, C; Barnett, S; Tomaras, GD; Ferrari, G; Montefiori, DC; Liao, H-X; Letvin, NL; Haynes, BF; Permar, SR, Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk., J Virol, vol 87 no. 12 (2013), pp. 6986-6999 [10.1128/JVI.00528-13] [abs].
  • Russell, ES; Ojeda, S; Fouda, GG; Meshnick, SR; Montefiori, D; Permar, SR; Swanstrom, R, Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes., Aids Res Hum Retroviruses, vol 29 no. 3 (2013), pp. 511-515 [10.1089/AID.2012.0197] [abs].
  • Fouda, GG; Mahlokozera, T; Salazar-Gonzalez, JF; Salazar, MG; Learn, G; Kumar, SB; Dennison, SM; Russell, E; Rizzolo, K; Jaeger, F; Cai, F; Vandergrift, NA; Gao, F; Hahn, B; Shaw, GM; Ochsenbauer, C; Swanstrom, R; Meshnick, S; Mwapasa, V; Kalilani, L; Fiscus, S; Montefiori, D; Haynes, B; Kwiek, J; Alam, SM; Permar, SR, Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants., Retrovirology, vol 10 (2013) [10.1186/1742-4690-10-3] [abs].
  • Handley, SA; Thackray, LB; Zhao, G; Presti, R; Miller, AD; Droit, L; Abbink, P; Maxfield, LF; Kambal, A; Duan, E; Stanley, K; Kramer, J; Macri, SC; Permar, SR; Schmitz, JE; Mansfield, K; Brenchley, JM; Veazey, RS; Stappenbeck, TS; Wang, D; Barouch, DH; Virgin, HW, Pathogenic simian immunodeficiency virus infection is associated with expansion of the enteric virome., Cell, vol 151 no. 2 (2012), pp. 253-266 [10.1016/j.cell.2012.09.024] [abs].
  • Schmitz, JE; Ma, Z-M; Hagan, EA; Wilks, AB; Furr, KL; Linde, CH; Zahn, RC; Brenchley, JM; Miller, CJ; Permar, SR, Memory CD4(+) T lymphocytes in the gastrointestinal tract are a major source of cell-associated simian immunodeficiency virus in chronic nonpathogenic infection of African green monkeys., J Virol, vol 86 no. 20 (2012), pp. 11380-11385 [10.1128/JVI.01556-12] [abs].
  • Amos, JD; Wilks, AB; Fouda, GG; Smith, SD; Overman, GR; Beck, K; Moody, MA; Tomaras, GD; Permar, SR, Strong SIV gp120-specific IgG/IgA responses in milk of African green monkeys may contribute to the rarity of postnatal transmission in this species, Retrovirology, vol 9 no. S2 (2012) [10.1186/1742-4690-9-s2-p198] [abs].
  • Parrish, NF; Wilen, CB; Banks, LB; Iyer, SS; Pfaff, JM; Salazar-Gonzalez, JF; Salazar, MG; Decker, JM; Parrish, EH; Berg, A; Hopper, J; Hora, B; Kumar, A; Mahlokozera, T; Yuan, S; Coleman, C; Vermeulen, M; Ding, H; Ochsenbauer, C; Tilton, JC; Permar, SR; Kappes, JC; Betts, MR; Busch, MP; Gao, F; Montefiori, D; Haynes, BF; Shaw, GM; Hahn, BH; Doms, RW, Transmitted/founder and chronic subtype C HIV-1 use CD4 and CCR5 receptors with equal efficiency and are not inhibited by blocking the integrin α4β7., Plos Pathog, vol 8 no. 5 (2012) [10.1371/journal.ppat.1002686] [abs].
  • Friedman, J; Alam, SM; Shen, X; Xia, S-M; Stewart, S; Anasti, K; Pollara, J; Fouda, GG; Yang, G; Kelsoe, G; Ferrari, G; Tomaras, GD; Haynes, BF; Liao, H-X; Moody, MA; Permar, SR, Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum., Plos One, vol 7 no. 5 (2012) [10.1371/journal.pone.0037648] [abs].
  • Fouda, G; Amos, J; Wilks, AB; Chand, A; Montefiori, D; Haynes, B; Letvin, N; Pickup, D; Liao, H; Permar, SR, Vaccine-elicited systemic and mucosal humoral responses of lactating rhesus monkeys vaccinated with the transmitted/founder HIV Envelope 1086C, Retrovirology, vol 9 no. Suppl 2 (2012), pp. O20-O20 [10.1186/1742-4690-9-s2-o20] [abs].
  • Ehlinger, EP; Webster, EM; Kang, HH; Cangialose, A; Simmons, AC; Barbas, KH; Burchett, SK; Gregory, ML; Puopolo, KM; Permar, SR, Maternal cytomegalovirus-specific immune responses and symptomatic postnatal cytomegalovirus transmission in very low-birth-weight preterm infants., J Infect Dis, vol 204 no. 11 (2011), pp. 1672-1682 [10.1093/infdis/jir632] [abs].
  • Wilks, AB; Perry, JR; Ehlinger, EP; Zahn, RC; White, R; Gauduin, M-C; Carville, A; Seaman, MS; Schmitz, JE; Permar, SR, High cell-free virus load and robust autologous humoral immune responses in breast milk of simian immunodeficiency virus-infected african green monkeys., J Virol, vol 85 no. 18 (2011), pp. 9517-9526 [10.1128/JVI.00796-11] [abs].
  • Fouda, GG; Yates, NL; Pollara, J; Shen, X; Overman, GR; Mahlokozera, T; Wilks, AB; Kang, HH; Salazar-Gonzalez, JF; Salazar, MG; Kalilani, L; Meshnick, SR; Hahn, BH; Shaw, GM; Lovingood, RV; Denny, TN; Haynes, B; Letvin, NL; Ferrari, G; Montefiori, DC; Tomaras, GD; Permar, SR; Center for HIV/AIDS Vaccine Immunology,, HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies., J Virol, vol 85 no. 18 (2011), pp. 9555-9567 [10.1128/JVI.05174-11] [abs].
  • Sun, Y; Asmal, M; Lane, S; Permar, SR; Schmidt, SD; Mascola, JR; Letvin, NL, Antibody-dependent cell-mediated cytotoxicity in simian immunodeficiency virus-infected rhesus monkeys., J Virol, vol 85 no. 14 (2011), pp. 6906-6912 [10.1128/JVI.00326-11] [abs].
  • Salazar-Gonzalez, JF; Salazar, MG; Learn, GH; Fouda, GG; Kang, HH; Mahlokozera, T; Wilks, AB; Lovingood, RV; Stacey, A; Kalilani, L; Meshnick, SR; Borrow, P; Montefiori, DC; Denny, TN; Letvin, NL; Shaw, GM; Hahn, BH; Permar, SR; Center for HIV/AIDS Vaccine Immunology A0167854,, Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing., J Virol, vol 85 no. 6 (2011), pp. 2751-2763 [10.1128/JVI.02316-10] [abs].
  • Mahlokozera, T; Kang, HH; Goonetilleke, N; Stacey, AR; Lovingood, RV; Denny, TN; Kalilani, L; Bunn, JEG; Meshnick, SR; Borrow, P; Letvin, NL; Permar, SR; Center for HIV/AIDS Vaccine Immunology,, The magnitude and kinetics of the mucosal HIV-specific CD8+ T lymphocyte response and virus RNA load in breast milk., Plos One, vol 6 no. 8 (2011) [10.1371/journal.pone.0023735] [abs].
  • Wilks, AB; Christian, EC; Seaman, MS; Sircar, P; Carville, A; Gomez, CE; Esteban, M; Pantaleo, G; Barouch, DH; Letvin, NL; Permar, SR, Robust vaccine-elicited cellular immune responses in breast milk following systemic simian immunodeficiency virus DNA prime and live virus vector boost vaccination of lactating rhesus monkeys., J Immunol, vol 185 no. 11 (2010), pp. 7097-7106 [10.4049/jimmunol.1002751] [abs].
  • Salazar-Gonzalez, JF; Salazar, MG; Learn, GH; Kang, HH; Mahlokozera, T; Kalilani, L; Meshnick, SR; Lovingood, RV; Denny, TN; Letvin, NL; Shaw, GM; Hahn, BH; Permar, SR, Local production of HIV variants in breast milk of chronically HIV-infected, lactating women, Aids Research and Human Retroviruses, vol 26 no. 10 (2010), pp. A148-A148 [abs].
  • Permar, SR; Wilks, AB; Ehlinger, EP; Kang, HH; Mahlokozera, T; Coffey, RT; Carville, A; Letvin, NL; Seaman, MS, Limited contribution of mucosal IgA to Simian immunodeficiency virus (SIV)-specific neutralizing antibody response and virus envelope evolution in breast milk of SIV-infected, lactating rhesus monkeys., J Virol, vol 84 no. 16 (2010), pp. 8209-8218 [10.1128/JVI.00656-10] [abs].
  • Permar, SR; Kang, HH; Wilks, AB; Mach, LV; Carville, A; Mansfield, KG; Learn, GH; Hahn, BH; Letvin, NL, Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys., Retrovirology, vol 7 (2010) [10.1186/1742-4690-7-7] [abs].
  • Permar, SR; Kang, HH; Wilks, AB; Mach, LV; Carville, A; Mansfield, KG; Learn, GH; Hahn, BH; Letvin, NL, Local replication of simian immunodeficiency virus in the breast milk compartment of chronically-infected, lactating rhesus monkeys, Retrovirology, vol 7 (2010) [10.1186/1742-4690-7-7] [abs].
  • Permar, SR; Kang, HH; Carville, A; Wilks, AB; Mansfield, KG; Rao, SS; Letvin, NL, Preservation of memory CD4(+) T lymphocytes in breast milk of lactating rhesus monkeys during acute simian immunodeficiency virus infection., J Infect Dis, vol 201 no. 2 (2010), pp. 302-310 [10.1086/649229] [abs].
  • Permar, SR; Kang, HH; Carville, A; Mansfield, KG; Gelman, RS; Rao, SS; Whitney, JB; Letvin, NL, Potent simian immunodeficiency virus-specific cellular immune responses in the breast milk of simian immunodeficiency virus-infected, lactating rhesus monkeys., J Immunol, vol 181 no. 5 (2008), pp. 3643-3650 [10.4049/jimmunol.181.5.3643] [abs].
  • Permar, SR; Rao, SS; Sun, Y; Bao, S; Buzby, AP; Kang, HH; Letvin, NL, Clinical measles after measles virus challenge in simian immunodeficiency virus-infected measles virus-vaccinated rhesus monkeys., The Journal of Infectious Diseases, vol 196 no. 12 (2007), pp. 1784-1793 [10.1086/522967] [abs].
  • Sun, Y; Permar, SR; Buzby, AP; Letvin, NL, Memory CD4+ T-lymphocyte loss and dysfunction during primary simian immunodeficiency virus infection., Journal of Virology, vol 81 no. 15 (2007), pp. 8009-8015 [10.1128/JVI.00482-07] [abs].
  • Permar, SR; Griffin, DE; Letvin, NL, Immune containment and consequences of measles virus infection in healthy and immunocompromised individuals., Clinical and Vaccine Immunology : Cvi, vol 13 no. 4 (2006), pp. 437-443 [10.1128/CVI.13.4.437-443.2006] [abs].
  • Permar, SR; Klumpp, SA; Mansfield, KG; Carville, AAL; Gorgone, DA; Lifton, MA; Schmitz, JE; Reimann, KA; Polack, FP; Griffin, DE; Letvin, NL, Limited contribution of humoral immunity to the clearance of measles viremia in rhesus monkeys., The Journal of Infectious Diseases, vol 190 no. 5 (2004), pp. 998-1005 [10.1086/422846] [abs].
  • Permar, SR; Moss, WJ; Ryon, JJ; Douek, DC; Monze, M; Griffin, DE, Increased thymic output during acute measles virus infection., Journal of Virology, vol 77 no. 14 (2003), pp. 7872-7879 [10.1128/jvi.77.14.7872-7879.2003] [abs].
  • Permar, SR; Klumpp, SA; Mansfield, KG; Kim, W-K; Gorgone, DA; Lifton, MA; Williams, KC; Schmitz, JE; Reimann, KA; Axthelm, MK; Polack, FP; Griffin, DE; Letvin, NL, Role of CD8(+) lymphocytes in control and clearance of measles virus infection of rhesus monkeys., Journal of Virology, vol 77 no. 7 (2003), pp. 4396-4400 [10.1128/jvi.77.7.4396-4400.2003] [abs].
  • Permar, SR; Moss, WJ; Ryon, JJ; Monze, M; Cutts, F; Quinn, TC; Griffin, DE, Prolonged measles virus shedding in human immunodeficiency virus-infected children, detected by reverse transcriptase-polymerase chain reaction., The Journal of Infectious Diseases, vol 183 no. 4 (2001), pp. 532-538 [10.1086/318533] [abs].