Rajan Tilak Gupta

Rajan Tilak Gupta

Professor of Radiology

Abdominal Imaging; Multiparametric MR imaging of prostate cancer; MR imaging of the hepatobiliary system; Applications of dual energy CT in the abdomen and pelvis

Appointments and Affiliations

  • Professor of Radiology
  • Professor in Urology
  • Member of the Duke Cancer Institute

Contact Information

  • Office Location: Department of Radiology, BOX_3808 Med Ctr, Durham, NC 27710
  • Office Phone: +1 919 684 7366
  • Email Address: rajan.gupta@duke.edu


  • M.D. Northwestern University, 2003

In the News

Representative Publications

  • Breault, SR; Heye, T; Bashir, MR; Dale, BM; Merkle, EM; Reiner, CS; Faridi, KF; Gupta, RT, Quantitative dynamic contrast-enhanced MRI of pelvic and lumbar bone marrow: effect of age and marrow fat content on pharmacokinetic parameter values., AJR Am J Roentgenol, vol 200 no. 3 (2013), pp. W297-W303 [10.2214/AJR.12.9080] [abs].
  • Bashir, MR; Gupta, RT; Davenport, MS; Allen, BC; Jaffe, TA; Ho, LM; Boll, DT; Merkle, EM, Hepatocellular carcinoma in a North American population: does hepatobiliary MR imaging with Gd-EOB-DTPA improve sensitivity and confidence for diagnosis?, J Magn Reson Imaging, vol 37 no. 2 (2013), pp. 398-406 [10.1002/jmri.23818] [abs].
  • Gupta, RT, Evaluation of the biliary tree and gallbladder with hepatocellular MR contrast agents., Curr Probl Diagn Radiol, vol 42 no. 2 (2013), pp. 67-76 [10.1067/j.cpradiol.2012.08.004] [abs].
  • Gupta, RT; Marin, D; Boll, DT; Husarik, DB; Davis, DE; Feuerlein, S; Merkle, EM, Hepatic hemangiomas: difference in enhancement pattern on 3T MR imaging with gadobenate dimeglumine versus gadoxetate disodium., Eur J Radiol, vol 81 no. 10 (2012), pp. 2457-2462 [10.1016/j.ejrad.2011.10.014] [abs].
  • Feuerlein, S; Gupta, RT; Boll, DT; Merkle, EM, Hepatocellular MR contrast agents: enhancement characteristics of liver parenchyma and portal vein after administration of gadoxetic acid in comparison to gadobenate dimeglumine., Eur J Radiol, vol 81 no. 9 (2012), pp. 2037-2041 [10.1016/j.ejrad.2011.06.014] [abs].
  • Bashir, MR; Dale, BM; Gupta, RT; Horvath, JJ; Boll, DT; Merkle, EM, Gradient shimming during magnetic resonance imaging of the liver: comparison of a standard protocol versus a novel reduced protocol., Invest Radiol, vol 47 no. 9 (2012), pp. 524-529 [10.1097/RLI.0b013e31825a8e5b] [abs].
  • Gupta, RT; Iseman, CM; Leyendecker, JR; Shyknevsky, I; Merkle, EM; Taouli, B, Diagnosis of focal nodular hyperplasia with MRI: multicenter retrospective study comparing gadobenate dimeglumine to gadoxetate disodium., AJR Am J Roentgenol, vol 199 no. 1 (2012), pp. 35-43 [10.2214/AJR.11.7757] [abs].
  • Krishnan, P; Gupta, RT; Boll, DT; Brady, CM; Husarik, DB; Merkle, EM, Functional evaluation of cystic duct patency with Gd-EOB-DTPA MR imaging: an alternative to hepatobiliary scintigraphy for diagnosis of acute cholecystitis?, Abdom Imaging, vol 37 no. 3 (2012), pp. 457-464 [10.1007/s00261-011-9785-y] [abs].
  • Bashir, MR; Gupta, RT, MDCT evaluation of the pancreas: nuts and bolts., Radiol Clin North Am, vol 50 no. 3 (2012), pp. 365-377 [10.1016/j.rcl.2012.03.012] [abs].
  • Ho, LM; Marin, D; Neville, AM; Barnhart, HX; Gupta, RT; Paulson, EK; Boll, DT, Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?, AJR Am J Roentgenol, vol 198 no. 4 (2012), pp. 840-845 [10.2214/AJR.11.7316] [abs].
  • Bashir, MR; Husarik, DB; Ziemlewicz, TJ; Gupta, RT; Boll, DT; Merkle, EM, Liver MRI in the hepatocyte phase with gadolinium-EOB-DTPA: does increasing the flip angle improve conspicuity and detection rate of hypointense lesions?, J Magn Reson Imaging, vol 35 no. 3 (2012), pp. 611-616 [10.1002/jmri.22850] [abs].
  • Husarik, DB; Gupta, RT; Ringe, KI; Boll, DT; Merkle, EM, Contrast enhanced liver MRI in patients with primary sclerosing cholangitis: inverse appearance of focal confluent fibrosis on delayed phase MR images with hepatocyte specific versus extracellular gadolinium based contrast agents., Acad Radiol, vol 18 no. 12 (2011), pp. 1549-1554 [10.1016/j.acra.2011.08.007] [abs].
  • Lungren, MP; Christensen, JD; Coleman, RE; Gupta, RT, PET appearance of tuberculous empyema necessitans., Clin Nucl Med, vol 36 no. 10 (2011), pp. 939-941 [10.1097/RLU.0b013e3182291bfd] [abs].
  • Ringe, KI; Husarik, DB; Gupta, RT; Boll, DT; Merkle, EM, Hepatobiliary transit times of gadoxetate disodium (Primovist®) for protocol optimization of comprehensive MR imaging of the biliary system--what is normal?, Eur J Radiol, vol 79 no. 2 (2011), pp. 201-205 [10.1016/j.ejrad.2010.03.008] [abs].
  • Miller, CM; Gupta, RT; Paulson, EK; Neville, AM; Bashir, MR; Merkle, EM; Boll, DT, Effect of organ enhancement and habitus on estimation of unenhanced attenuation at contrast-enhanced dual-energy MDCT: concepts for individualized and organ-specific spectral iodine subtraction strategies., AJR Am J Roentgenol, vol 196 no. 5 (2011), pp. W558-W564 [10.2214/AJR.10.4858] [abs].
  • Neville, AM; Gupta, RT; Miller, CM; Merkle, EM; Paulson, EK; Boll, DT, Detection of renal lesion enhancement with dual-energy multidetector CT., Radiology, vol 259 no. 1 (2011), pp. 173-183 [10.1148/radiol.10101170] [abs].
  • Feuerlein, S; Boll, DT; Gupta, RT; Ringe, KI; Marin, D; Merkle, EM, Gadoxetate disodium-enhanced hepatic MRI: dose-dependent contrast dynamics of hepatic parenchyma and portal vein., AJR Am J Roentgenol, vol 196 no. 1 (2011), pp. W18-W24 [10.2214/AJR.10.4387] [abs].
  • Gupta, RT; Brady, CM; Lotz, J; Boll, DT; Merkle, EM, Dynamic MR imaging of the biliary system using hepatocyte-specific contrast agents., AJR Am J Roentgenol, vol 195 no. 2 (2010), pp. 405-413 [10.2214/AJR.09.3641] [abs].
  • Gupta, RT; Ho, LM; Marin, D; Boll, DT; Barnhart, HX; Nelson, RC, Dual-energy CT for characterization of adrenal nodules: initial experience., AJR Am J Roentgenol, vol 194 no. 6 (2010), pp. 1479-1483 [10.2214/AJR.09.3476] [abs].
  • Ringe, KI; Gupta, RT; Brady, CM; Massey, CM; Hahn, A; Galanski, M; Merkle, EM; Lotz, J, Respiratory-triggered three-dimensional T2-weighted MR cholangiography after injection of gadoxetate disodium: is it still reliable?, Radiology, vol 255 no. 2 (2010), pp. 451-458 [10.1148/radiol.10091130] [abs].
  • Coursey, CA; Nelson, RC; Boll, DT; Paulson, EK; Ho, LM; Neville, AM; Marin, D; Gupta, RT; Schindera, ST, Dual-energy multidetector CT: how does it work, what can it tell us, and when can we use it in abdominopelvic imaging?, Radiographics, vol 30 no. 4 (2010), pp. 1037-1055 [10.1148/rg.304095175] [abs].
  • Gupta, RT; Kakarla, RK; Kirshenbaum, KJ; Tapson, VF, D-dimers and efficacy of clinical risk estimation algorithms: sensitivity in evaluation of acute pulmonary embolism., AJR Am J Roentgenol, vol 193 no. 2 (2009), pp. 425-430 [10.2214/AJR.08.2186] [abs].
  • Gupta, RT; Wadhwa, RP; Learch, TJ; Herwick, SM, Lisfranc injury: imaging findings for this important but often-missed diagnosis., Curr Probl Diagn Radiol, vol 37 no. 3 (2008), pp. 115-126 [10.1067/j.cpradiol.2007.08.012] [abs].