Purushothama Rao Tata

Purushothama Rao Tata

Assistant Professor of Cell Biology

Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology

Appointments and Affiliations

  • Assistant Professor of Cell Biology
  • Affiliate of the Regeneration Next Initiative
  • Member of the Duke Cancer Institute

Contact Information

Education

  • Ph.D. University of Ulm (Germany), 2011

Courses Taught

  • CELLBIO 493: Research Independent Study
  • CMB 710D: Cell & Molecular Biology Module IV

In the News

Representative Publications

  • Delorey, TM; Ziegler, CGK; Heimberg, G; Normand, R; Yang, Y; Segerstolpe, A; Abbondanza, D; Fleming, SJ; Subramanian, A; Montoro, DT; Jagadeesh, KA; Dey, KK; Sen, P; Slyper, M; Pita-Juárez, YH; Phillips, D; Bloom-Ackerman, Z; Barkas, N; Ganna, A; Gomez, J; Normandin, E; Naderi, P; Popov, YV; Raju, SS; Niezen, S; Tsai, LT-Y; Siddle, KJ; Sud, M; Tran, VM; Vellarikkal, SK; Amir-Zilberstein, L; Atri, DS; Beechem, J; Brook, OR; Chen, J; Divakar, P; Dorceus, P; Engreitz, JM; Essene, A; Fitzgerald, DM; Fropf, R; Gazal, S; Gould, J; Grzyb, J; Harvey, T; Hecht, J; Hether, T; Jane-Valbuena, J; Leney-Greene, M; Ma, H; McCabe, C; McLoughlin, DE; Miller, EM; Muus, C; Niemi, M; Padera, R; Pan, L; Pant, D; Pe'er, C; Pfiffner-Borges, J; Pinto, CJ; Plaisted, J; Reeves, J; Ross, M; Rudy, M; Rueckert, EH; Siciliano, M; Sturm, A; Todres, E; Waghray, A; Warren, S; Zhang, S; Zollinger, DR; Cosimi, L; Gupta, RM; Hacohen, N; Hide, W; Price, AL; Rajagopal, J; Tata, PR; Riedel, S; Szabo, G; Tickle, TL; Hung, D; Sabeti, PC; Novak, R; Rogers, R; Ingber, DE; Gordon Jiang, Z; Juric, D; Babadi, M; Farhi, SL; Stone, JR; Vlachos, IS; Solomon, IH; Ashenberg, O; Porter, CBM; Li, B; Shalek, AK; Villani, A-C; Rozenblatt-Rosen, O; Regev, A, A single-cell and spatial atlas of autopsy tissues reveals pathology and cellular targets of SARS-CoV-2., Biorxiv (2021) [10.1101/2021.02.25.430130] [abs].
  • Moiseenko, A; Vazquez-Armendariz, AI; Kheirollahi, V; Chu, X; Tata, A; Rivetti, S; Günther, S; Lebrigand, K; Herold, S; Braun, T; Mari, B; De Langhe, S; Kwapiszewska, G; Günther, A; Chen, C; Seeger, W; Tata, PR; Zhang, J-S; Bellusci, S; El Agha, E, Identification of a Repair-Supportive Mesenchymal Cell Population during Airway Epithelial Regeneration., Cell Reports, vol 33 no. 12 (2020) [10.1016/j.celrep.2020.108549] [abs].
  • Okuda, K; Dang, H; Kobayashi, Y; Carraro, G; Nakano, S; Chen, G; Kato, T; Asakura, T; Gilmore, RC; Morton, LC; Lee, RE; Mascenik, T; Yin, W-N; Barbosa Cardenas, SM; O'Neal, YK; Minnick, CE; Chua, M; Quinney, NL; Gentzsch, M; Anderson, CW; Ghio, A; Matsui, H; Nagase, T; Ostrowski, LE; Grubb, BR; Olsen, JC; Randell, SH; Stripp, BR; Tata, PR; O'Neal, WK; Boucher, RC, Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia., American Journal of Respiratory and Critical Care Medicine (2020) [10.1164/rccm.202008-3198OC] [abs].
  • Bernardes, JP; Mishra, N; Tran, F; Bahmer, T; Best, L; Blase, JI; Bordoni, D; Franzenburg, J; Geisen, U; Josephs-Spaulding, J; Köhler, P; Künstner, A; Rosati, E; Aschenbrenner, AC; Bacher, P; Baran, N; Boysen, T; Brandt, B; Bruse, N; Dörr, J; Dräger, A; Elke, G; Ellinghaus, D; Fischer, J; Forster, M; Franke, A; Franzenburg, S; Frey, N; Friedrichs, A; Fuß, J; Glück, A; Hamm, J; Hinrichsen, F; Hoeppner, MP; Imm, S; Junker, R; Kaiser, S; Kan, YH; Knoll, R; Lange, C; Laue, G; Lier, C; Lindner, M; Marinos, G; Markewitz, R; Nattermann, J; Noth, R; Pickkers, P; Rabe, KF; Renz, A; Röcken, C; Rupp, J; Schaffarzyk, A; Scheffold, A; Schulte-Schrepping, J; Schunk, D; Skowasch, D; Ulas, T; Wandinger, K-P; Wittig, M; Zimmermann, J; Busch, H; Hoyer, BF; Kaleta, C; Heyckendorf, J; Kox, M; Rybniker, J; Schreiber, S; Schultze, JL; Rosenstiel, P; HCA Lung Biological Network, ; Deutsche COVID-19 Omics Initiative (DeCOI),, Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19., Immunity, vol 53 no. 6 (2020), pp. 1296-1314.e9 [10.1016/j.immuni.2020.11.017] [abs].
  • Katsura, H; Sontake, V; Tata, A; Kobayashi, Y; Edwards, CE; Heaton, BE; Konkimalla, A; Asakura, T; Mikami, Y; Fritch, EJ; Lee, PJ; Heaton, NS; Boucher, RC; Randell, SH; Baric, RS; Tata, PR, Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction., Cell Stem Cell, vol 27 no. 6 (2020), pp. 890-904.e8 [10.1016/j.stem.2020.10.005] [abs].