Purushothama Rao Tata

Purushothama Rao Tata

Assistant Professor of Cell Biology

Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology

Appointments and Affiliations

  • Assistant Professor of Cell Biology
  • Assistant Professor in Medicine
  • Member of the Duke Cancer Institute
  • Affiliate of the Duke Regeneration Center

Contact Information


  • Ph.D. University of Ulm (Germany), 2011

Awards, Honors, and Distinctions

  • Rising Star Award. International Society for Regenerative Biology. 2022
  • Whitehead Scholar Award. Duke University School of Medicine. 2016
  • NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
  • The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014

Courses Taught

  • CELLBIO 493: Research Independent Study
  • CELLBIO 730: Stem Cell Course
  • CMB 710D: Cell & Molecular Biology Module IV
  • CMB 710E: Cell & Molecular Biology Module V
  • DSCB 720: Stem Cell Course
  • MOLCAN 730: Stem Cell Course
  • PHARM 730: Stem Cell Course

In the News

Representative Publications

  • Karmaus, PWF; Tata, A; Meacham, JM; Day, F; Thrower, D; Tata, PR; Fessler, MB, Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates., Am J Respir Cell Mol Biol, vol 69 no. 6 (2023), pp. 623-637 [10.1165/rcmb.2023-0077OC] [abs].
  • Vazquez-Armendariz, AI; Tata, PR, Recent advances in lung organoid development and applications in disease modeling., J Clin Invest, vol 133 no. 22 (2023) [10.1172/JCI170500] [abs].
  • Konkimalla, A; Konishi, S; Macadlo, L; Kobayashi, Y; Farino, ZJ; Miyashita, N; El Haddad, L; Morowitz, J; Barkauskas, CE; Agarwal, P; Souma, T; ElMallah, MK; Tata, A; Tata, PR, Transitional cell states sculpt tissue topology during lung regeneration., Cell Stem Cell, vol 30 no. 11 (2023), pp. 1486-1502.e9 [10.1016/j.stem.2023.10.001] [abs].
  • Hou, YJ; Chiba, S; Leist, SR; Meganck, RM; Martinez, DR; Schäfer, A; Catanzaro, NJ; Sontake, V; West, A; Edwards, CE; Yount, B; Lee, RE; Gallant, SC; Zost, SJ; Powers, J; Adams, L; Kong, EF; Mattocks, M; Tata, A; Randell, SH; Tata, PR; Halfmann, P; Crowe, JE; Kawaoka, Y; Baric, RS, Host range, transmissibility and antigenicity of a pangolin coronavirus., Nature Microbiology, vol 8 no. 10 (2023), pp. 1820-1833 [10.1038/s41564-023-01476-x] [abs].
  • El Haddad, L; Lai, E; Murthy, PKL; Biswas, DD; Soufny, R; Roger, AL; Tata, PR; ElMallah, MK, GAA deficiency disrupts distal airway cells in Pompe disease., Am J Physiol Lung Cell Mol Physiol, vol 325 no. 3 (2023), pp. L288-L298 [10.1152/ajplung.00032.2023] [abs].