Purushothama Rao Tata

Purushothama Rao Tata

Assistant Professor of Cell Biology

Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology

Appointments and Affiliations

  • Assistant Professor of Cell Biology
  • Assistant Professor in Medicine
  • Member of the Duke Cancer Institute
  • Affiliate of the Duke Regeneration Center

Contact Information


  • Ph.D. University of Ulm (Germany), 2011

Awards, Honors, and Distinctions

  • Rising Star Award. International Society for Regenerative Biology. 2022
  • Whitehead Scholar Award. Duke University School of Medicine. 2016
  • NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
  • The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014

Courses Taught

  • CELLBIO 493: Research Independent Study
  • CELLBIO 730: Stem Cell Course
  • CMB 710D: Cell & Molecular Biology Module IV
  • MOLCAN 730: Stem Cell Course
  • PHARM 730: Stem Cell Course

In the News

Representative Publications

  • Konishi, S; Tata, A; Tata, PR, Defined conditions for long-term expansion of murine and human alveolar epithelial stem cells in three-dimensional cultures., Star Protocols, vol 3 no. 2 (2022) [10.1016/j.xpro.2022.101447] [abs].
  • Leinroth, AP; Mirando, AJ; Rouse, D; Kobayahsi, Y; Tata, PR; Rueckert, HE; Liao, Y; Long, JT; Chakkalakal, JV; Hilton, MJ, Identification of distinct non-myogenic skeletal-muscle-resident mesenchymal cell populations., Cell Reports, vol 39 no. 6 (2022) [10.1016/j.celrep.2022.110785] [abs].
  • El Haddad, L; Lai, E; Murthy, P; Tata, PR; ElMallah, MK, GAA Deficiency Disrupts Distal Airway Cells in Pompe Disease, Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, vol 36 (2022) [10.1096/fasebj.2022.36.S1.L7829] [abs].
  • Kadur Lakshminarasimha Murthy, P; Sontake, V; Tata, A; Kobayashi, Y; Macadlo, L; Okuda, K; Conchola, AS; Nakano, S; Gregory, S; Miller, LA; Spence, JR; Engelhardt, JF; Boucher, RC; Rock, JR; Randell, SH; Tata, PR, Human distal lung maps and lineage hierarchies reveal a bipotent progenitor., Nature, vol 604 no. 7904 (2022), pp. 111-119 [10.1038/s41586-022-04541-3] [abs].
  • Kadur Lakshminarasimha Murthy, P; Xi, R; Arguijo, D; Everitt, JI; Kocak, DD; Kobayashi, Y; Bozec, A; Vicent, S; Ding, S; Crawford, GE; Hsu, D; Tata, PR; Reddy, T; Shen, X, Epigenetic basis of oncogenic-Kras-mediated epithelial-cellular proliferation and plasticity., Dev Cell, vol 57 no. 3 (2022), pp. 310-328.e9 [10.1016/j.devcel.2022.01.006] [abs].