Purushothama Rao Tata

Purushothama Rao Tata

Assistant Professor of Cell Biology

Lung regeneration
Lung stem cells
Cell plasticity
Organoid models
Lung Fibrosis
Single Cell Biology

Appointments and Affiliations

  • Assistant Professor of Cell Biology
  • Affiliate of the Regeneration Next Initiative
  • Member of the Duke Cancer Institute

Contact Information

Education

  • Ph.D. University of Ulm (Germany), 2011

Courses Taught

  • CELLBIO 493: Research Independent Study
  • CMB 710D: Cell & Molecular Biology Module IV

In the News

Representative Publications

  • Heaton, BE; Trimarco, JD; Hamele, CE; Harding, AT; Tata, A; Zhu, X; Tata, PR; Smith, CM; Heaton, NS, SRSF protein kinases 1 and 2 are essential host factors for human coronaviruses including SARS-CoV-2., Biorxiv (2020) [10.1101/2020.08.14.251207] [abs].
  • Kobayashi, Y; Tata, A; Konkimalla, A; Katsura, H; Lee, RF; Ou, J; Banovich, NE; Kropski, JA; Tata, PR, Persistence of a regeneration-associated, transitional alveolar epithelial cell state in pulmonary fibrosis., Nat Cell Biol, vol 22 no. 8 (2020), pp. 934-946 [10.1038/s41556-020-0542-8] [abs].
  • Hou, YJ; Okuda, K; Edwards, CE; Martinez, DR; Asakura, T; Dinnon, KH; Kato, T; Lee, RE; Yount, BL; Mascenik, TM; Chen, G; Olivier, KN; Ghio, A; Tse, LV; Leist, SR; Gralinski, LE; Schäfer, A; Dang, H; Gilmore, R; Nakano, S; Sun, L; Fulcher, ML; Livraghi-Butrico, A; Nicely, NI; Cameron, M; Cameron, C; Kelvin, DJ; de Silva, A; Margolis, DM; Markmann, A; Bartelt, L; Zumwalt, R; Martinez, FJ; Salvatore, SP; Borczuk, A; Tata, PR; Sontake, V; Kimple, A; Jaspers, I; O'Neal, WK; Randell, SH; Boucher, RC; Baric, RS, SARS-CoV-2 Reverse Genetics Reveals a Variable Infection Gradient in the Respiratory Tract., Cell, vol 182 no. 2 (2020), pp. 429-446.e14 [10.1016/j.cell.2020.05.042] [abs].
  • Ziegler, CGK; Allon, SJ; Nyquist, SK; Mbano, IM; Miao, VN; Tzouanas, CN; Cao, Y; Yousif, AS; Bals, J; Hauser, BM; Feldman, J; Muus, C; Wadsworth, MH; Kazer, SW; Hughes, TK; Doran, B; Gatter, GJ; Vukovic, M; Taliaferro, F; Mead, BE; Guo, Z; Wang, JP; Gras, D; Plaisant, M; Ansari, M; Angelidis, I; Adler, H; Sucre, JMS; Taylor, CJ; Lin, B; Waghray, A; Mitsialis, V; Dwyer, DF; Buchheit, KM; Boyce, JA; Barrett, NA; Laidlaw, TM; Carroll, SL; Colonna, L; Tkachev, V; Peterson, CW; Yu, A; Zheng, HB; Gideon, HP; Winchell, CG; Lin, PL; Bingle, CD; Snapper, SB; Kropski, JA; Theis, FJ; Schiller, HB; Zaragosi, L-E; Barbry, P; Leslie, A; Kiem, H-P; Flynn, JL; Fortune, SM; Berger, B; Finberg, RW; Kean, LS; Garber, M; Schmidt, AG; Lingwood, D; Shalek, AK; Ordovas-Montanes, J; HCA Lung Biological Network. Electronic address: lung-network@humancellatlas.org, ; HCA Lung Biological Network,, SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues., Cell, vol 181 no. 5 (2020), pp. 1016-1035.e19 [10.1016/j.cell.2020.04.035] [abs].
  • Sungnak, W; Huang, N; Bécavin, C; Berg, M; Queen, R; Litvinukova, M; Talavera-López, C; Maatz, H; Reichart, D; Sampaziotis, F; Worlock, KB; Yoshida, M; Barnes, JL; HCA Lung Biological Network,, SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes., Nat Med, vol 26 no. 5 (2020), pp. 681-687 [10.1038/s41591-020-0868-6] [abs].