Purushothama Rao Tata

Assistant Professor of Cell Biology

Appointments and Affiliations

• Assistant Professor of Cell Biology
• Assistant Professor in Medicine
• Member of the Duke Cancer Institute
• Affiliate of the Duke Regeneration Center

Contact Information

• Email Address: purushothamarao.tata@duke.edu
• Websites:
  • Tata lab
  • www.cellbio.duke.edu/purushothama-rao-tata

Education

• Ph.D. University of Ulm (Germany), 2011

Awards, Honors, and Distinctions

• Rising Star Award. International Society for Regenerative Biology. 2022
• Whitehead Scholar Award. Duke University School of Medicine. 2016
• NIH K99-Pathways to Independence Award. National Institutes of Health. 2015
• The Fund for Medical Discovery (FMD) Research Award. Massachusetts General Hospital. 2014

Courses Taught

• CELLBIO 493: Research Independent Study
• CELLBIO 730: Stem Cell Course
• CMB 710D: Cell & Molecular Biology Module IV
• CMB 710E: Cell & Molecular Biology Module V
• DSCB 720: Stem Cell Course
• MOLCAN 730: Stem Cell Course
• PHARM 730: Stem Cell Course

In the News

• Study Provides Clues to Developing Better Treatments for Lung Damage (Nov 15, 2023 | School of Medicine)
• Tata to Receive International Society for Regenerative Biology Rising Star Award (Jul 20, 2022)
• NIH-Directors blog- Mini-Lungs in a Lab Dish Mimic Early COVID-19 Infection (Nov 19, 2020 | NIH-Directors blog)
• Lab-Grown Mini-Lungs Mimic the Real Thing – Right Down to Covid Infection (Oct 22, 2020)
• SARS-CoV-2 Targets Many Cell Types, Analysis of Single-Cell Data Suggests (May 11, 2020 | www.hhmi.org)
• Scientists Find Stomach Cells In Lung Cancer (Mar 26, 2018)
• Purushothama Tata: So Many Ideas, So Little Time (Oct 2, 2016)

Representative Publications

• Karmaus, PWF; Tata, A; Meacham, JM; Day, F; Thrower, D; Tata, PR; Fessler, MB, Meta-Analysis of COVID-19 BAL Single-Cell RNA Sequencing Reveals Alveolar Epithelial Transitions and Unique Alveolar Epithelial Cell Fates., Am J Respir Cell Mol Biol, vol 69 no. 6 (2023), pp. 623-637 [10.1165/rcmb.2023-0077OC] [abs].
• Vazquez-Armendariz, AI; Tata, PR, Recent advances in lung organoid development and applications in disease modeling., J Clin Invest, vol 133 no. 22 (2023) [10.1172/JCI170500] [abs].
• Konkimalla, A; Konishi, S; Macadlo, L; Kobayashi, Y; Farino, ZJ; Miyashita, N; El Haddad, L; Morowitz, J; Barkauskas, CE; Agarwal, P; Souma, T; ElMallah, MK; Tata, A; Tata, PR, Transitional cell states sculpt tissue topology during lung regeneration., Cell Stem Cell, vol 30 no. 11 (2023), pp. 1486-1502.e9 [10.1016/j.stem.2023.10.001] [abs].
• Hou, YJ; Chiba, S; Leist, SR; Meganck, RM; Martinez, DR; Schäfer, A; Catanzaro, NJ; Sontake, V; West, A; Edwards, CE; Yount, B; Lee, RE; Gallant, SC; Zost, SJ; Powers, J; Adams, L; Kong, EF; Mattocks, M; Tata, A; Randell, SH; Tata, PR; Halfmann, P; Crowe, JE; Kawaoka, Y; Baric, RS, Host range, transmissibility and antigenicity of a pangolin coronavirus., Nature Microbiology, vol 8 no. 10 (2023), pp. 1820-1833 [10.1038/s41564-023-01476-x] [abs].
• El Haddad, L; Lai, E; Murthy, PKL; Biswas, DD; Soufny, R; Roger, AL; Tata, PR; ElMallah, MK, GAA deficiency disrupts distal airway cells in Pompe disease., Am J Physiol Lung Cell Mol Physiol, vol 325 no. 3 (2023), pp. L288-L298 [10.1152/ajplung.00032.2023] [abs].