Nicholas Scott Heaton

Assistant Professor of Molecular Genetics and Microbiology

Appointments and Affiliations

Sniffing Out COVID-Related Loss of Smell (Jan 11, 2021 | Duke Health News)
Scent-Sensing Cells Have a Better Way to Fight Flu (Sep 1, 2020)
Lung Cell Patches Its Own DNA on the Fly to Survive Influenza (Jul 29, 2019)
Microbiology Society Recognizes Two Duke Researchers (Sep 6, 2018)
New Vaccine Production Could Improve Flu Shot Accuracy (Jul 24, 2017)

Katsura, H; Sontake, V; Tata, A; Kobayashi, Y; Edwards, CE; Heaton, BE; Konkimalla, A; Asakura, T; Mikami, Y; Fritch, EJ; Lee, PJ; Heaton, NS; Boucher, RC; Randell, SH; Baric, RS; Tata, PR, Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction., Cell Stem Cell, vol 27 no. 6 (2020), pp. 890-904.e8 [10.1016/j.stem.2020.10.005] [abs].
Froggatt, HM; Heaton, BE; Heaton, NS, Development of a Fluorescence-Based, High-Throughput SARS-CoV-2 3CLpro Reporter Assay., J Virol, vol 94 no. 22 (2020) [10.1128/JVI.01265-20] [abs].
Dumm, RE; Wellford, SA; Moseman, EA; Heaton, NS, Heterogeneity of Antiviral Responses in the Upper Respiratory Tract Mediates Differential Non-lytic Clearance of Influenza Viruses., Cell Reports, vol 32 no. 9 (2020) [10.1016/j.celrep.2020.108103] [abs].
Abbott, TR; Dhamdhere, G; Liu, Y; Lin, X; Goudy, L; Zeng, L; Chemparathy, A; Chmura, S; Heaton, NS; Debs, R; Pande, T; Endy, D; La Russa, MF; Lewis, DB; Qi, LS, Development of CRISPR as an Antiviral Strategy to Combat SARS-CoV-2 and Influenza., Cell, vol 181 no. 4 (2020), pp. 865-876.e12 [10.1016/j.cell.2020.04.020] [abs].
Chambers, BS; Heaton, BE; Rausch, K; Dumm, RE; Hamilton, JR; Cherry, S; Heaton, NS, DNA mismatch repair is required for the host innate response and controls cellular fate after influenza virus infection., Nature Microbiology, vol 4 no. 11 (2019), pp. 1964-1977 [10.1038/s41564-019-0509-3] [abs].