Lisa Deneen Hobson-Webb

Lisa Deneen Hobson-Webb

Professor of Neurology

Trained in neuromuscular medicine, my clinical career has focused on the care of patients with genetically mediated neuromuscular disorders, rare peripheral neuropathies, and immune-mediated nerve and muscle disorders and performing high quality electrodiagnostic testing (nerve conduction studies/electromyography). As a researcher, the core aim of my work is applying high resolution ultrasound in the care of patients with neuromuscular diseases.  My early work focused on peripheral nerve and is now moving toward muscle imaging.  My current research includes muscle ultrasound in late onset Pompe disease and peripheral nerve imaging in acute inflammatory demyelinating radiculoneuropathy.  Since 2016, I have collaborated with Dr. Kathryn Nightingale’s biomedical engineering laboratory on applying shear wave imaging to diseases of the nerve and muscle.   I am interested in clinical trials for neuromuscular disorders and novel technologies for diagnosing and monitoring neuromuscular disease.


Appointments and Affiliations

  • Professor of Neurology
  • Vice Chair, Clinical Operations in the Department of Neurology

Contact Information

  • Office Location: Dept of Medicine, Division of Neurology, Durham, NC 27710
  • Office Phone: +1 919 668 2277
  • Email Address:


  • Duke University, 2007
  • Wake Forest University, 2005
  • Wake Forest University, 2002
  • M.D. University of Kentucky, College of Medicine, 2001

Representative Publications

  • Li, Y; Yi, JS; Guptill, JT; Juel, VC; Hobson-Webb, L; Raja, SM; Karatz, T; Gable, KL, Immune dysregulation in chronic inflammatory demyelinating polyneuropathy., J Neuroimmunol, vol 391 (2024) [10.1016/j.jneuroim.2024.578360] [abs].
  • Narayanaswami, P; Sanders, DB; Thomas, L; Thibault, D; Blevins, J; Desai, R; Krueger, A; Bibeau, K; Liu, B; Guptill, JT; PROMISE-MG Study Group, , Comparative effectiveness of azathioprine and mycophenolate mofetil for myasthenia gravis (PROMISE-MG): a prospective cohort study., Lancet Neurol, vol 23 no. 3 (2024), pp. 267-276 [10.1016/S1474-4422(24)00028-0] [abs].
  • Paley, CT; Knight, AE; Jin, FQ; Moavenzadeh, SR; Rouze, NC; Pietrosimone, LS; Hobson-Webb, LD; Palmeri, ML; Nightingale, KR, Rotational 3D shear wave elasticity imaging: Effect of knee flexion on 3D shear wave propagation in in vivo vastus lateralis., J Mech Behav Biomed Mater, vol 150 (2024) [10.1016/j.jmbbm.2023.106302] [abs].
  • Tawfik, EA; Cartwright, MS; van Alfen, N; Axer, H; Boon, AJ; Crump, N; Grimm, A; Hobson-Webb, LD; Kerasnoudis, A; Mandeville, R; Preston, DC; Sakamuri, S; Shahrizaila, N; Shin, S; Shook, SJ; Wilder-Smith, E; Walker, FO, Neuromuscular ultrasound standardized scanning techniques and protocols: Expert panel recommendations., Muscle Nerve, vol 68 no. 4 (2023), pp. 375-379 [10.1002/mus.27830] [abs].
  • , Erratum for “Ultrasound‐guided electromyography in plegic muscle: Usefulness of nerve stimulation”, Muscle & Nerve, vol 68 no. 2 (2023) [10.1002/mus.27920] [abs].