Howard Levinson

Howard Levinson

Associate Professor of Surgery

Fibrosis
Wound Healing
Cell Contractility
Tissue Remodeling
Medical device development including hernia mesh, tissue engineered skin and wound care technologies

Appointments and Affiliations

  • Associate Professor of Surgery
  • Associate Professor in Pathology
  • Associate Professor in Dermatology
  • Core Faculty in Innovation & Entrepreneurship

Contact Information

  • Office Location: Dept of Surgery, Durham, NC 27710
  • Office Phone: (919) 684-8661
  • Email Address: howard.levinson@duke.edu

Education

  • M.D. University of Texas, Medical Branch at Galveston, 1997

Courses Taught

  • PATHOL 293: Research Independent Study
  • PATHOL 793: Research Independent Study

In the News

Representative Publications

  • Bond, JE; Ho, TQ; Selim, MA; Hunter, CL; Bowers, EV; Levinson, H, Temporal spatial expression and function of non-muscle myosin II isoforms IIA and IIB in scar remodeling., Lab Invest, vol 91 no. 4 (2011), pp. 499-508 [10.1038/labinvest.2010.181] [abs].
  • Komatsu, I; Bond, J; Selim, A; Tomasek, JJ; Levin, LS; Levinson, H, Dupuytren's fibroblast contractility by sphingosine-1-phosphate is mediated through non-muscle myosin II., J Hand Surg Am, vol 35 no. 10 (2010), pp. 1580-1588 [10.1016/j.jhsa.2010.07.009] [abs].
  • Yang, J; Erdmann, D; Chang, JC; Komatsu, I; Zhang, Y; Wang, D; Hodavance, MS; Hollenbeck, ST; Levinson, H; Klitzman, B; Levin, LS, A model of sequential heart and composite tissue allotransplant in rats., Plast Reconstr Surg, vol 126 no. 1 (2010), pp. 80-86 [10.1097/PRS.0b013e3181dbbb64] [abs].
  • Fearmonti, R; Bond, J; Erdmann, D; Levinson, H, A review of scar scales and scar measuring devices., Eplasty, vol 10 (2010) [abs].
  • Hillyer, S; Vicens, JC; Levinson, H; Bhayani, R; Mesea, L; Chaudhry, R; Fayans, E; Fogler, R, Alveolar soft-part sarcoma of the tongue in a 17-month-old., Ear Nose Throat J, vol 88 no. 10 (2009), pp. E4-E9 [abs].
  • Lee, CC; Golub, R; Singer, AJ; Cantu, R; Levinson, H, Routine versus selective abdominal computed tomography scan in the evaluation of right lower quadrant pain: a randomized controlled trial., Acad Emerg Med, vol 14 no. 2 (2007), pp. 117-122 [10.1197/j.aem.2006.08.007] [abs].
  • Khyrul, WAKM; LaLonde, DP; Brown, MC; Levinson, H; Turner, CE, The integrin-linked kinase regulates cell morphology and motility in a rho-associated kinase-dependent manner., The Journal of Biological Chemistry, vol 279 no. 52 (2004), pp. 54131-54139 [10.1074/jbc.M410051200] [abs].
  • Levinson, H; Moyer, KE; Saggers, GC; Ehrlich, HP, Calmodulin-myosin light chain kinase inhibition changes fibroblast-populated collagen lattice contraction, cell migration, focal adhesion formation, and wound contraction., Wound Repair and Regeneration, vol 12 no. 5 (2004), pp. 505-511 [10.1111/j.1067-1927.2004.012502.x] [abs].
  • Levinson, H; Sil, AK; Conwell, JE; Hopper, JE; Ehrlich, HP, Alpha V integrin prolongs collagenase production through Jun activation binding protein 1., Annals of Plastic Surgery, vol 53 no. 2 (2004), pp. 155-161 [10.1097/01.sap.0000112281.97409.a6] [abs].
  • Levinson, H; Turner, CE; Ehrlich, HP, Integrin-linked kinase: a possible role in scar contracture., Annals of Plastic Surgery, vol 52 no. 2 (2004), pp. 204-211 [10.1097/01.sap.0000100893.35542.f6] [abs].
  • Levinson, H; Hopper, JE; Ehrlich, HP, Overexpression of integrin alphav promotes human osteosarcoma cell populated collagen lattice contraction and cell migration., Journal of Cellular Physiology, vol 193 no. 2 (2002), pp. 219-224 [10.1002/jcp.10164] [abs].
  • Levinson, H; Peled, Z; Liu, W; Longaker, MT; Allison, GM; Ehrlich, HP, Fetal rat amniotic fluid: transforming growth factor beta and fibroblast collagen lattice contraction., Journal of Surgical Research, vol 100 no. 2 (2001), pp. 205-210 [10.1006/jsre.2001.6243] [abs].
  • Chin, GS; Lee, S; Hsu, M; Liu, W; Kim, WJ; Levinson, H; Longaker, MT, Discoidin domain receptors and their ligand, collagen, are temporally regulated in fetal rat fibroblasts in vitro., Plastic and Reconstructive Surgery, vol 107 no. 3 (2001), pp. 769-776 [10.1097/00006534-200103000-00018] [abs].
  • Chin, GS; Liu, W; Steinbrech, D; Hsu, M; Levinson, H; Longaker, MT, Cellular signaling by tyrosine phosphorylation in keloid and normal human dermal fibroblasts., Plastic and Reconstructive Surgery, vol 106 no. 7 (2000), pp. 1532-1540 [10.1097/00006534-200012000-00014] [abs].
  • Chin, GS; Kim, WJ; Lee, TY; Liu, W; Saadeh, PB; Lee, S; Levinson, H; Gittes, GK; Longaker, MT, Differential expression of receptor tyrosine kinases and Shc in fetal and adult rat fibroblasts: toward defining scarless versus scarring fibroblast phenotypes., Plastic and Reconstructive Surgery, vol 105 no. 3 (2000), pp. 972-979 [10.1097/00006534-200003000-00021] [abs].