Genevieve Giny Fouda

Genevieve Giny Fouda

Associate Professor in Pediatrics

Dr Fouda's research interest is in understanding infant immune responses in the setting of infection and vaccination. Her current work focuses on HIV mother to child transmission.

Appointments and Affiliations

  • Associate Professor in Pediatrics
  • Assistant Research Professor in the Department of Molecular Genetics and Microbiology
  • Member of the Duke Human Vaccine Institute

Contact Information

  • Office Location: MSRBII, Durham, NC 27710
  • Office Phone: (919) 681-0608
  • Email Address: genevieve.fouda@duke.edu

Education

  • Ph.D. Georgetown University, 2006
  • M.D. University of Yaoundé I (Cameroon), 2002

In the News

Representative Publications

  • Pollara, J; McGuire, E; Fouda, GG; Rountree, W; Eudailey, J; Overman, RG; Seaton, KE; Deal, A; Edwards, RW; Tegha, G; Kamwendo, D; Kumwenda, J; Nelson, JAE; Liao, H-X; Brinkley, C; Denny, TN; Ochsenbauer, C; Ellington, S; King, CC; Jamieson, DJ; van der Horst, C; Kourtis, AP; Tomaras, GD; Ferrari, G; Permar, SR, Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1., J Virol, vol 89 no. 19 (2015), pp. 9952-9961 [10.1128/JVI.01560-15] [abs].
  • Shen, X; Duffy, R; Howington, R; Cope, A; Sadagopal, S; Park, H; Pal, R; Kwa, S; Ding, S; Yang, OO; Fouda, GG; Le Grand, R; Bolton, D; Esteban, M; Phogat, S; Roederer, M; Amara, RR; Picker, LJ; Seder, RA; McElrath, MJ; Barnett, S; Permar, SR; Shattock, R; DeVico, AL; Felber, BK; Pavlakis, GN; Pantaleo, G; Korber, BT; Montefiori, DC; Tomaras, GD, Vaccine-Induced Linear Epitope-Specific Antibodies to Simian Immunodeficiency Virus SIVmac239 Envelope Are Distinct from Those Induced to the Human Immunodeficiency Virus Type 1 Envelope in Nonhuman Primates., J Virol, vol 89 no. 16 (2015), pp. 8643-8650 [10.1128/JVI.03635-14] [abs].
  • Permar, SR; Fong, Y; Vandergrift, N; Fouda, GG; Gilbert, P; Parks, R; Jaeger, FH; Pollara, J; Martelli, A; Liebl, BE; Lloyd, K; Yates, NL; Overman, RG; Shen, X; Whitaker, K; Chen, H; Pritchett, J; Solomon, E; Friberg, E; Marshall, DJ; Whitesides, JF; Gurley, TC; Von Holle, T; Martinez, DR; Cai, F; Kumar, A; Xia, S-M; Lu, X; Louzao, R; Wilkes, S; Datta, S; Sarzotti-Kelsoe, M; Liao, H-X; Ferrari, G; Alam, SM; Montefiori, DC; Denny, TN; Moody, MA; Tomaras, GD; Gao, F; Haynes, BF, Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission., J Clin Invest, vol 125 no. 7 (2015), pp. 2702-2706 [10.1172/JCI81593] [abs].
  • Fouda, GG; Moody, MA; Permar, SR, Antibodies for prevention of mother-to-child transmission of HIV-1., Curr Opin Hiv Aids, vol 10 no. 3 (2015), pp. 177-182 [10.1097/COH.0000000000000150] [abs].
  • Fouda, GG; Cunningham, CK; Permar, SR, Infant HIV-1 vaccines: supplementing strategies to reduce maternal-child transmission., Jama, vol 313 no. 15 (2015), pp. 1513-1514 [10.1001/jama.2015.1382] [abs].
  • Sacha, CR; Vandergrift, N; Jeffries, TL; McGuire, E; Fouda, GG; Liebl, B; Marshall, DJ; Gurley, TC; Stiegel, L; Whitesides, JF; Friedman, J; Badiabo, A; Foulger, A; Yates, NL; Tomaras, GD; Kepler, TB; Liao, HX; Haynes, BF; Moody, MA; Permar, SR, Restricted isotype, distinct variable gene usage, and high rate of gp120 specificity of HIV-1 envelope-specific B cells in colostrum compared with those in blood of HIV-1-infected, lactating African women., Mucosal Immunol, vol 8 no. 2 (2015), pp. 316-326 [10.1038/mi.2014.69] [abs].
  • Fouda, GG; Cunningham, CK; McFarland, EJ; Borkowsky, W; Muresan, P; Pollara, J; Song, LY; Liebl, BE; Whitaker, K; Shen, X; Vandergrift, NA; Overman, RG; Yates, NL; Moody, MA; Fry, C; Kim, JH; Michael, NL; Robb, M; Pitisuttithum, P; Kaewkungwal, J; Nitayaphan, S; Rerks-Ngarm, S; Liao, H-X; Haynes, BF; Montefiori, DC; Ferrari, G; Tomaras, GD; Permar, SR, Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses., J Infect Dis, vol 211 no. 4 (2015), pp. 508-517 [10.1093/infdis/jiu444] [abs].
  • Fouda, GG; Permar, SR, Immune-based interventions to prevent postnatal HIV-1 transmission., Trends Microbiol, vol 22 no. 8 (2014), pp. 425-427 [10.1016/j.tim.2014.04.009] [abs].
  • Fouda, GG; Jaeger, FH; Amos, JD; Ho, C; Kunz, EL; Anasti, K; Stamper, LW; Liebl, BE; Barbas, KH; Ohashi, T; Moseley, MA; Liao, H-X; Erickson, HP; Alam, SM; Permar, SR, Tenascin-C is an innate broad-spectrum, HIV-1-neutralizing protein in breast milk., Proc Natl Acad Sci U S A, vol 110 no. 45 (2013), pp. 18220-18225 [10.1073/pnas.1307336110] [abs].
  • Amos, JD; Wilks, AB; Fouda, GG; Smith, SD; Colvin, L; Mahlokozera, T; Ho, C; Beck, K; Overman, RG; DeMarco, CT; Hodge, TL; LaBranche, CC; Montefiori, DC; Denny, TN; Liao, H-X; Tomaras, GD; Moody, MA; Permar, SR, Lack of B cell dysfunction is associated with functional, gp120-dominant antibody responses in breast milk of simian immunodeficiency virus-infected African green monkeys., J Virol, vol 87 no. 20 (2013), pp. 11121-11134 [10.1128/JVI.01887-13] [abs].
  • Fouda, GGA; Amos, JD; Wilks, AB; Pollara, J; Ray, CA; Chand, A; Kunz, EL; Liebl, BE; Whitaker, K; Carville, A; Smith, S; Colvin, L; Pickup, DJ; Staats, HF; Overman, G; Eutsey-Lloyd, K; Parks, R; Chen, H; Labranche, C; Barnett, S; Tomaras, GD; Ferrari, G; Montefiori, DC; Liao, H-X; Letvin, NL; Haynes, BF; Permar, SR, Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk., J Virol, vol 87 no. 12 (2013), pp. 6986-6999 [10.1128/JVI.00528-13] [abs].
  • Russell, ES; Ojeda, S; Fouda, GG; Meshnick, SR; Montefiori, D; Permar, SR; Swanstrom, R, Short communication: HIV type 1 subtype C variants transmitted through the bottleneck of breastfeeding are sensitive to new generation broadly neutralizing antibodies directed against quaternary and CD4-binding site epitopes., Aids Res Hum Retroviruses, vol 29 no. 3 (2013), pp. 511-515 [10.1089/AID.2012.0197] [abs].
  • Fouda, GG; Mahlokozera, T; Salazar-Gonzalez, JF; Salazar, MG; Learn, G; Kumar, SB; Dennison, SM; Russell, E; Rizzolo, K; Jaeger, F; Cai, F; Vandergrift, NA; Gao, F; Hahn, B; Shaw, GM; Ochsenbauer, C; Swanstrom, R; Meshnick, S; Mwapasa, V; Kalilani, L; Fiscus, S; Montefiori, D; Haynes, B; Kwiek, J; Alam, SM; Permar, SR, Postnatally-transmitted HIV-1 Envelope variants have similar neutralization-sensitivity and function to that of nontransmitted breast milk variants., Retrovirology, vol 10 (2013) [10.1186/1742-4690-10-3] [abs].
  • Friedman, J; Alam, SM; Shen, X; Xia, S-M; Stewart, S; Anasti, K; Pollara, J; Fouda, GG; Yang, G; Kelsoe, G; Ferrari, G; Tomaras, GD; Haynes, BF; Liao, H-X; Moody, MA; Permar, SR, Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum., Plos One, vol 7 no. 5 (2012) [10.1371/journal.pone.0037648] [abs].
  • Fouda, GG; Yates, NL; Pollara, J; Shen, X; Overman, GR; Mahlokozera, T; Wilks, AB; Kang, HH; Salazar-Gonzalez, JF; Salazar, MG; Kalilani, L; Meshnick, SR; Hahn, BH; Shaw, GM; Lovingood, RV; Denny, TN; Haynes, B; Letvin, NL; Ferrari, G; Montefiori, DC; Tomaras, GD; Permar, SR; Center for HIV/AIDS Vaccine Immunology,, HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies., J Virol, vol 85 no. 18 (2011), pp. 9555-9567 [10.1128/JVI.05174-11] [abs].
  • Salazar-Gonzalez, JF; Salazar, MG; Learn, GH; Fouda, GG; Kang, HH; Mahlokozera, T; Wilks, AB; Lovingood, RV; Stacey, A; Kalilani, L; Meshnick, SR; Borrow, P; Montefiori, DC; Denny, TN; Letvin, NL; Shaw, GM; Hahn, BH; Permar, SR; Center for HIV/AIDS Vaccine Immunology A0167854,, Origin and evolution of HIV-1 in breast milk determined by single-genome amplification and sequencing., J Virol, vol 85 no. 6 (2011), pp. 2751-2763 [10.1128/JVI.02316-10] [abs].