David Samuel Warner

Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine
Appointments and Affiliations
- Distinguished Distinguished Professor of Anesthesiology, in the School of Medicine
- Professor of Anesthesiology
- Vice-Chair, Research
- Chief, Division of Basic Sciences
- Professor in Neurobiology
- Professor of Surgery
- Faculty Network Member of the Duke Institute for Brain Sciences
Contact Information
- Office Location: 303 Research Dr., 134 Sands Buildign, Durham, NC 27710
- Office Phone: (919) 684-6633
- Email Address: david.warner@duke.edu
Education
- M.D. University of Wisconsin - Madison, 1980
Awards, Honors, and Distinctions
- Award For Translational Research Mentoring. Duke University School of Medicine. 2015
- Award for Mentoring Excellence in Research. Foundation for Anesthesia Education and Research (American Society of Anesthesiologists). 2015
- Distinguished Alumnus Award for Achievement. University of Iowa Carver College of Medicine. 2015
- Distinguished Service Award. Society for Neurosciences In Anesthesiology and Critical Care. 2011
- Neuroscience Award. Azzociazione Per La Diffusione E L'Avanzamento Delle Neuroscienze Toscano. 2011
- Teacher Of The Year. Department of Anesthesiology, DUMC. 2011
- Excellence in Research. American Society of Anesthesiologists. 2005
Representative Publications
- Yates, RB; Sheng, H; Sakai, H; Kleven, DT; DeSimone, NA; Stafford-Smith, M; Warner, DS, Lack of evidence for a remote effect of renal ischemia/reperfusion acute kidney injury on outcome from temporary focal cerebral ischemia in the rat., J Cardiothorac Vasc Anesth, vol 27 no. 1 (2013), pp. 71-78 [10.1053/j.jvca.2012.06.012] [abs].
- Tovmasyan, A; Sheng, H; Weitner, T; Arulpragasam, A; Lu, M; Warner, DS; Vujaskovic, Z; Spasojevic, I; Batinic-Haberle, I, Design, mechanism of action, bioavailability and therapeutic effects of mn porphyrin-based redox modulators., Medical Principles and Practice : International Journal of the Kuwait University, Health Science Centre, vol 22 no. 2 (2013), pp. 103-130 [10.1159/000341715] [abs].
- Topjian, AA; Berg, RA; Bierens, JJLM; Branche, CM; Clark, RS; Friberg, H; Hoedemaekers, CWE; Holzer, M; Katz, LM; Knape, JTA; Kochanek, PM; Nadkarni, V; van der Hoeven, JG; Warner, DS, Brain resuscitation in the drowning victim., Neurocritical Care, vol 17 no. 3 (2012), pp. 441-467 [10.1007/s12028-012-9747-4] [abs].
- Rajic, Z; Tovmasyan, A; Spasojevic, I; Sheng, H; Lu, M; Li, AM; Gralla, EB; Warner, DS; Benov, L; Batinic-Haberle, I, A new SOD mimic, Mn(III) ortho N-butoxyethylpyridylporphyrin, combines superb potency and lipophilicity with low toxicity., Free Radic Biol Med, vol 52 no. 9 (2012), pp. 1828-1834 [10.1016/j.freeradbiomed.2012.02.006] [abs].
- Indraswari, F; Wang, H; Lei, B; James, ML; Kernagis, D; Warner, DS; Dawson, HN; Laskowitz, DT, Statins improve outcome in murine models of intracranial hemorrhage and traumatic brain injury: a translational approach., J Neurotrauma, vol 29 no. 7 (2012), pp. 1388-1400 [10.1089/neu.2011.2117] [abs].
- Sheng, H; Spasojevic, I; Tse, HM; Jung, JY; Hong, J; Zhang, Z; Piganelli, JD; Batinic-Haberle, I; Warner, DS, Neuroprotective efficacy from a lipophilic redox-modulating Mn(III) N-Hexylpyridylporphyrin, MnTnHex-2-PyP: rodent models of ischemic stroke and subarachnoid hemorrhage., Journal of Pharmacology and Experimental Therapeutics, vol 338 no. 3 (2011), pp. 906-916 [10.1124/jpet.110.176701] [abs].
- Tovmasyan, AG; Rajic, Z; Spasojevic, I; Reboucas, JS; Chen, X; Salvemini, D; Sheng, H; Warner, DS; Benov, L; Batinic-Haberle, I, Methoxy-derivatization of alkyl chains increases the in vivo efficacy of cationic Mn porphyrins. Synthesis, characterization, SOD-like activity, and SOD-deficient E. coli study of meta Mn(III) N-methoxyalkylpyridylporphyrins., Dalton Trans, vol 40 no. 16 (2011), pp. 4111-4121 [10.1039/c0dt01321h] [abs].
- Sheng, H; Reynolds, JD; Auten, RL; Demchenko, IT; Piantadosi, CA; Stamler, JS; Warner, DS, Pharmacologically augmented S-nitrosylated hemoglobin improves recovery from murine subarachnoid hemorrhage., Stroke; a Journal of Cerebral Circulation, vol 42 no. 2 (2011), pp. 471-476 [10.1161/STROKEAHA.110.600569] [abs].
- Guinn, NR; McDonagh, DL; Borel, CO; Wright, DR; Zomorodi, AR; Powers, CJ; Warner, DS; Lam, AM; Britz, GW, Adenosine-induced transient asystole for intracranial aneurysm surgery: a retrospective review., J Neurosurg Anesthesiol, vol 23 no. 1 (2011), pp. 35-40 [10.1097/ANA.0b013e3181ef2b11] [abs].
- Wang, Z; Yang, W; Britz, GW; Lombard, FW; Warner, DS; Sheng, H, Development of a simplified spinal cord ischemia model in mice., J Neurosci Methods, vol 189 no. 2 (2010), pp. 246-251 [10.1016/j.jneumeth.2010.04.003] [abs].
- Pearlstein, RD; Higuchi, Y; Moldovan, M; Johnson, K; Fukuda, S; Gridley, DS; Crapo, JD; Warner, DS; Slater, JM, Metalloporphyrin antioxidants ameliorate normal tissue radiation damage in rat brain., Int J Radiat Biol, vol 86 no. 2 (2010), pp. 145-163 [10.3109/09553000903419965] [abs].
- Sheng, H; Yang, W; Fukuda, S; Tse, HM; Paschen, W; Johnson, K; Batinic-Haberle, I; Crapo, JD; Pearlstein, RD; Piganelli, J; Warner, DS, Long-term neuroprotection from a potent redox-modulating metalloporphyrin in the rat., Free Radic Biol Med, vol 47 no. 7 (2009), pp. 917-923 [10.1016/j.freeradbiomed.2009.05.039] [abs].
- Takata, K; Sheng, H; Borel, CO; Laskowitz, DT; Warner, DS; Lombard, FW, Simvastatin treatment duration and cognitive preservation in experimental subarachnoid hemorrhage., J Neurosurg Anesthesiol, vol 21 no. 4 (2009), pp. 326-333 [10.1097/ANA.0b013e3181acfde7] [abs].
- Mackensen, GB; McDonagh, DL; Warner, DS, Perioperative hypothermia: use and therapeutic implications., J Neurotrauma, vol 26 no. 3 (2009), pp. 342-358 [10.1089/neu.2008.0596] [abs].