Andrew Paul Landstrom

Andrew Paul Landstrom

Associate Professor of Pediatrics

Dr. Landstrom is a physician scientist who specializes in the care of children and young adults with arrhythmias, heritable cardiovascular diseases, and sudden unexplained death syndromes. As a clinician, he is trained in pediatric cardiology with a focus on arrhythmias and genetic diseases of the heart.  He specializes in caring for patients with heritable arrhythmia (channelopathies) such as long QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia, and short QT syndrome.  He also specializes in the evaluation of children following a cardiac arrest or after the sudden and unexplained death of a family member.  He has expertise in cardiovascular genetics and uses it to identify individuals in a family who may be at risk of a disease, even if all clinical testing is negative.  As a scientist, he is trained in genetics and cell biology.  He runs a research lab exploring the genetic and molecular causes of arrhythmias, sudden unexplained death syndromes, and heart muscle disease (cardiomyopathies).  He utilizes patient-derived induced pluripotent stem cells and genetic mouse models to identify the mechanisms of cardiovascular genetic disease with the goal of developing novel therapies.

Appointments and Affiliations

  • Associate Professor of Pediatrics
  • Director of the Duke Pediatric Research Scholars Program for Physician-Scientist Development
  • Associate Professor in Cell Biology

Contact Information

  • Office Location: Duke University Medical Center, Box 2652, Durham, NC 27710
  • Office Phone: (919) 684-3028
  • Email Address:
  • Websites:


  • American Board of Pediatrics, 2099
  • Baylor College of Medicine, 2018
  • American Board of Pediatrics, 2099
  • Baylor College of Medicine, 2017
  • Baylor College of Medicine, 2018
  • Baylor College of Medicine, 2014
  • Baylor College of Medicine, 2013
  • Ph.D. Mayo School of Health Sciences, 2012
  • M.D. Mayo School of Health Sciences, 2012

Awards, Honors, and Distinctions

  • Fellow. Heart Rhythm Society. 2020
  • Fellow. American Heart Association. 2019
  • Fellow. Society for Pediatric Research. 2019
  • Young Investigator Award. American Heart Association, Council on Cardiovascular Disease in the Young. 2018
  • Best Poster Award. Baylor College of Medicine 6th Annual Cardiovascular Research Institute Symposium. 2017
  • Dan G. McNamara Fellow of the Year Award. Baylor College of Medicine, Dept of Pediatrics, Section of Cardiology. 2017
  • Top Abstract Award. Baylor College of Medicine 5th Annual Cardiovascular Research Institute Symposium. 2016
  • Outstanding Fellow in Pediatrics. Baylor College of Medicine, Dept of Pediatrics House Officers. 2015
  • Adam Cohen Professionalism Award. Baylor College of Medicine, Dept of Pediatrics . 2014
  • Distinguished Educator Award. Baylor College of Medicine, Dept of Pediatrics. 2014
  • Jan Goddard-Finegold Award in Developmental Pediatrics. Baylor College of Medicine, Dept of Pediatrics. 2014
  • Gold Humanism in Medicine Honor Society Inductee. Baylor College of Medicine. 2013

Courses Taught

  • BIOLOGY 293: Research Independent Study
  • BIOLOGY 493: Research Independent Study
  • CELLBIO 493: Research Independent Study

In the News

Representative Publications

  • Shah, RA; Asatryan, B; Sharaf Dabbagh, G; Aung, N; Khanji, MY; Lopes, LR; van Duijvenboden, S; Holmes, A; Muser, D; Landstrom, AP; Lee, AM; Arora, P; Semsarian, C; Somers, VK; Owens, AT; Munroe, PB; Petersen, SE; Chahal, CAA; Genotype-First Approach Investigators,, Frequency, Penetrance, and Variable Expressivity of Dilated Cardiomyopathy-Associated Putative Pathogenic Gene Variants in UK Biobank Participants., Circulation, vol 146 no. 2 (2022), pp. 110-124 [10.1161/CIRCULATIONAHA.121.058143] [abs].
  • Rosamilia, MB; Lu, IM; Landstrom, AP, Pathogenicity Assignment of Variants in Genes Associated With Cardiac Channelopathies Evolve Toward Diagnostic Uncertainty., Circulation. Genomic and Precision Medicine, vol 15 no. 3 (2022) [10.1161/CIRCGEN.121.003491] [abs].
  • Scherba, JC; Halushka, MK; Andersen, ND; Maleszewski, JJ; Landstrom, AP; Bursac, N; Glass, C, BRG1 is a biomarker of hypertrophic cardiomyopathy in human heart specimens., Scientific Reports, vol 12 no. 1 (2022) [10.1038/s41598-022-11829-x] [abs].
  • Meester, JAN; Peeters, S; Van Den Heuvel, L; Vandeweyer, G; Fransen, E; Cappella, E; Dietz, HC; Forbus, G; Gelb, BD; Goldmuntz, E; Hoskoppal, A; Landstrom, AP; Lee, T; Mital, S; Morris, S; Olson, AK; Renard, M; Roden, DM; Singh, MN; Selamet Tierney, ES; Tretter, JT; Van Driest, SL; Willing, M; Verstraeten, A; Van Laer, L; Lacro, RV; Loeys, BL, Molecular characterization and investigation of the role of genetic variation in phenotypic variability and response to treatment in a large pediatric Marfan syndrome cohort., Genet Med, vol 24 no. 5 (2022), pp. 1045-1053 [10.1016/j.gim.2021.12.015] [abs].
  • Parker, LE; Wallace, K; Thevathasan, A; Funk, E; Pratt, M; Thamby, J; Tran, L; Prange, L; Uchitel, J; Boggs, A; Minton, M; Jasien, J; Nagao, KJ; Richards, A; Cruse, B; De-Lisle Dear, G; Landstrom, AP; Mikati, MA, Characterization of sedation and anesthesia complications in patients with alternating hemiplegia of childhood., Eur J Paediatr Neurol, vol 38 (2022), pp. 47-52 [10.1016/j.ejpn.2022.03.007] [abs].