Warren M. Grill

Image of Warren M. Grill

Professor of Biomedical Engineering

Our research employs engineering approaches to understand and control neural function. We work on fundamental questions and applied development in electrical stimulation of the nervous system to restore function to individuals with neurological impairment or injury.

Current projects include:
• understanding the mechanisms of and developing advanced approaches to deep brain stimulation to treat movement disorders,
• developing novel approaches to peripheral nerve electrical stimulation for restoration of bladder function, 
• understanding the mechanisms of and developing advanced approaches to spinal cord stimulation to treat chronic pain,
• understanding and controlling the cellular effects of transcranial magnetic stimulation, and
• design of novel electrodes and waveforms for selective stimulation of the nervous system.

Appointments and Affiliations

  • Professor of Biomedical Engineering
  • Edmund T. Pratt, Jr. School Professor of Biomedical Engineering
  • Bass Fellow
  • Affiliate of the Duke Initiative for Science & Society
  • Professor in Neurobiology
  • Professor in Neurosurgery
  • Professor in the Department of Electrical and Computer Engineering
  • Faculty Network Member of the Duke Institute for Brain Sciences

Contact Information:

Education:

  • Ph.D. Case Western Reserve University, 1995
  • M.S. Case Western Reserve University, 1992
  • B.S. Boston University, 1989

Awards, Honors, and Distinctions:

  • Javits Neuroscience Investigator Award. NIH-NINDS . 2015
  • Scholar / Teacher of the Year Award. Duke University. 2014
  • Outstanding Postdoc Mentor. Duke University. 2013
  • Fellow. Biomedical Engineering Society. 2011
  • Fellow. American Institute for Medical and Biological Engineering. 2007

Courses Taught:

  • BME 301L: Bioelectricity (AC or GE)
  • BME 394: Projects in Biomedical Engineering (GE)
  • BME 493: Projects in Biomedical Engineering (GE)
  • BME 494: Projects in Biomedical Engineering (GE)
  • BME 504: Fundamentals of Electrical Stimulation of the Nervous System (GE, EL)
  • BME 515: Neural Prosthetic Systems (GE, EL, IM)
  • BME 790L: Advanced Topics with the Lab for Graduate Students in Biomedical Engineering
  • BME 791: Graduate Independent Study
  • NEUROSCI 301L: Bioelectricity (AC or GE)
  • NEUROSCI 504: Fundamentals of Electrical Stimulation of the Nervous System (GE, EL)
  • NEUROSCI 515: Neural Prosthetic Systems (GE, EL, IM)

Representative Publications:

    • Cassar, IR; Titus, ND; Grill, WM, An improved genetic algorithm for designing optimal temporal patterns of neural stimulation., Journal of Neural Engineering, vol 14 no. 6 (2017) [10.1088/1741-2552/aa8270] [abs].
    • Barth, BB; Henriquez, CS; Grill, WM; Shen, X, Electrical stimulation of gut motility guided by an in silico model., Journal of Neural Engineering, vol 14 no. 6 (2017) [10.1088/1741-2552/aa86c8] [abs].
    • Hokanson, JA; Langdale, CL; Sridhar, A; Grill, WM, Stimulation of the Sensory Pudendal Nerve Increases Bladder Capacity in the Rat., American Journal of Physiology: Renal Physiology (2017) [10.1152/ajprenal.00373.2017] [abs].
    • Hokanson, JA; Langdale, CL; Sridhar, A; Grill, WM, OAB without an overactive bladder in the acute prostaglandin E2 rat model., American Journal of Physiology: Renal Physiology, vol 313 no. 5 (2017), pp. F1169-F1177 [10.1152/ajprenal.00270.2017] [abs].
    • McGee, MJ; Swan, BD; Danziger, ZC; Amundsen, CL; Grill, WM, Multiple Reflex Pathways Contribute to Bladder Activation by Intraurethral Stimulation in Persons With Spinal Cord Injury., Urology, vol 109 (2017), pp. 210-215 [10.1016/j.urology.2017.07.041] [abs].