Gregory M. Palmer

Image of Gregory M. Palmer

Associate Professor of Radiation Oncology

Greg Palmer obtained his B.S. in Biomedical Engineering from Marquette University in 2000, after which he obtained his Ph.D. in BME from the University of Wisconsin, Madison. He is currently an Associate Professor in the Department of Radiation Oncology, Cancer Biology Division at Duke University Medical Center. His primary research focus has been identifying and exploiting the changes in absorption, scattering, and fluorescence properties of tissue associated with cancer progression and therapeutic response. To this end he has implemented a model-based approach for extracting absorber and scatterer properties from diffuse reflectance and fluorescence measurements. More recently he has developed quantitative imaging methodologies for intravital microscopy to characterize tumor functional and molecular response to radiation and chemotherapy. His awards have included the Jack Fowler Award from the Radiation Research Society.

Laboratory Website:
https://radonc.duke.edu/research-education/research-labs/radiation-and-cancer-biology/palmer-lab

Appointments and Affiliations

  • Associate Professor of Radiation Oncology
  • Member of the Duke Cancer Institute

Contact Information:

Education:

  • Ph.D. University of Wisconsin at Madison, 2005

Courses Taught:

  • MEDPHY 507: Radiation Biology
  • MEDPHY 791K: Independent Study in Medical Physics

Representative Publications:

    • Juhas, M; Engelmayr, GC; Fontanella, AN; Palmer, GM; Bursac, N, Biomimetic engineered muscle with capacity for vascular integration and functional maturation in vivo., Proceedings of the National Academy of Sciences of USA, vol 111 no. 15 (2014), pp. 5508-5513 [10.1073/pnas.1402723111] [abs].
    • Palmer, GM; Fontanella, AN; Shan, S; Hanna, G; Zhang, G; Fraser, CL; Dewhirst, MW, In vivo optical molecular imaging and analysis in mice using dorsal window chamber models applied to hypoxia, vasculature and fluorescent reporters., Nature Protocols, vol 6 no. 9 (2011), pp. 1355-1366 [10.1038/nprot.2011.349] [abs].
    • Chitneni, SK; Palmer, GM; Zalutsky, MR; Dewhirst, MW, Molecular imaging of hypoxia., Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol 52 no. 2 (2011), pp. 165-168 [10.2967/jnumed.110.075663] [abs].
    • Palmer, GM; Fontanella, AN; Zhang, G; Hanna, G; Fraser, CL; Dewhirst, MW, Optical imaging of tumor hypoxia dynamics., Journal of Biomedical Optics, vol 15 no. 6 (2010) [10.1117/1.3523363] [abs].
    • Palmer, GM; Boruta, RJ; Viglianti, BL; Lan, L; Spasojevic, I; Dewhirst, MW, Non-invasive monitoring of intra-tumor drug concentration and therapeutic response using optical spectroscopy., Journal of Controlled Release, vol 142 no. 3 (2010), pp. 457-464 [10.1016/j.jconrel.2009.10.034] [abs].
    • Zhang, G; Palmer, GM; Dewhirst, MW; Fraser, CL, A dual-emissive-materials design concept enables tumour hypoxia imaging., Nature Materials, vol 8 no. 9 (2009), pp. 747-751 [10.1038/nmat2509] [abs].
    • Palmer, GM; Viola, RJ; Schroeder, T; Yarmolenko, PS; Dewhirst, MW; Ramanujam, N, Quantitative diffuse reflectance and fluorescence spectroscopy: tool to monitor tumor physiology in vivo., Journal of Biomedical Optics, vol 14 no. 2 (2009) [10.1117/1.3103586] [abs].
    • Palmer, GM; Ramanujam, N, Monte-Carlo-based model for the extraction of intrinsic fluorescence from turbid media., Journal of Biomedical Optics, vol 13 no. 2 (2008) [10.1117/1.2907161] [abs].
    • Palmer, GM; Ramanujam, N, Use of genetic algorithms to optimize fiber optic probe design for the extraction of tissue optical properties., IEEE Transactions on Biomedical Engineering, vol 54 no. 8 (2007), pp. 1533-1535 [10.1109/TBME.2006.889779] [abs].
    • Palmer, GM; Ramanujam, N, Monte Carlo-based inverse model for calculating tissue optical properties. Part I: Theory and validation on synthetic phantoms., Applied Optics, vol 45 no. 5 (2006), pp. 1062-1071 [abs].
    • Palmer, GM; Zhu, C; Breslin, TM; Xu, F; Gilchrist, KW; Ramanujam, N, Monte Carlo-based inverse model for calculating tissue optical properties. Part II: Application to breast cancer diagnosis., Applied Optics, vol 45 no. 5 (2006), pp. 1072-1078 [abs].
    • Palmer, GM; Zhu, C; Breslin, TM; Xu, F; Gilchrist, KW; Ramanujam, N, Comparison of multiexcitation fluorescence and diffuse reflectance spectroscopy for the diagnosis of breast cancer (March 2003)., IEEE Transactions on Biomedical Engineering, vol 50 no. 11 (2003), pp. 1233-1242 [10.1109/TBME.2003.818488] [abs].